Results 101 to 110 of about 92,981 (315)
Scalable Biophysical Simulations of the Neuromuscular System [PDF]
arXiv, 2021 The human neuromuscular system consisting of skeletal muscles and neural circuits is a complex system that is not yet fully understood. Surface electromyography (EMG) can be used to study muscle behavior from the outside. Computer simulations with detailed biophysical models provide a non-invasive tool to interpret EMG signals and gain new insights ...
arxiv
Journal of Pharmacy and Pharmacology, 1959 AbstractPreliminary observations upon a series of NNNN-tetra-onium compounds (Ia to Ih), an NNSNN-penta-onium compound (II) and an NNNNNN-hexa-onium compound (III) have so far indicated that inter-onium distance is more important in determining the type of activity than the overall length of the molecule or the number of onium centres it contains.
D. Edwards +3 more
openaire +2 more sources
Newer Neuromuscular Blocking Agents [PDF]
Pharmacology & Toxicology, 1994 Four neuromuscular blocking drugs, doxacurium, mivacurium, pipecuronium, and rocuronium have been or are about to be introduced into clinical practice. The purpose of this MiniReview is to describe their pharmacology, to consider their place in clinical anaesthetic practice, and to examine whether the needs of the clinican have been met.
openaire +3 more sources
Tetanus Toxin, a Neuromuscular Blocking Agent [PDF]
Nature, 1969 IN some cases of infectious tetanus a neuromuscular block with tetraplegia may follow the state of muscle spasms. We suggested1 that this effect was caused by the tetanus toxin itself rather than to an after-effect of muscle relaxants or other drugs. This hypothesis, however, had to be verified by experiments with animals.
H. E. Kaeser, A. Saner
openaire +3 more sources
Design, Modeling, and Control of a Soft Robotic Diaphragm‐Assist Device in a Respiratory Simulator
Advanced Intelligent Systems, EarlyView.A soft robotic diaphragm‐assist device using fabric‐based pneumatic actuators with a 2‐step control system to optimize synchronization and support is introduced. This system can detect the initiation of breathing to trigger assistance and regulate pressures to provide the correct level of inhalation augmentation. Validation and testing are completed on
Diego Quevedo‐Moreno +5 more
wiley +1 more source
Rule Based Expert System for Diagnosis of Neuromuscular Disorders [PDF]
arXiv, 2012 In this paper, we discuss the implementation of a rule based expert system for diagnosing neuromuscular diseases. The proposed system is implemented as a rule based expert system in JESS for the diagnosis of Cerebral Palsy, Multiple Sclerosis, Muscular Dystrophy and Parkinson's disease. In the system, the user is presented with a list of questionnaires
arxiv
Advanced Intelligent Systems, EarlyView.In this contribution, it is shown that miniaturized nerve stimulation implants can be used in collaborative networks. Inductive links and ultrasound are combined to supply these implants with energy and data; the advantages and disadvantages of each method, as well as safety risks and possibilities for improvement are discussed and the best ...
Benedikt Szabo +5 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive pathogenic variants in both alleles. Additionally, depending on the mechanisms by which UPD occurs, mosaic aneuploidies may
Marta Carreño‐Hidalgo +4 more
wiley +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Annals of Neurology, EarlyView.Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel +10 more
wiley +1 more source
Annals of Neurology, EarlyView.Neuropsychiatric diseases are common among forcibly displaced persons, and a better understanding is needed to improve screening and treatment efforts. We performed a retrospective cross‐sectional study at a single academic center looking at neuropsychiatric diagnoses of United States resettled refugees presenting for their domestic medical examination.
Noor F. Shaik +2 more
wiley +1 more source