Results 41 to 50 of about 82,250 (244)
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +2 more sources
Newer Neuromuscular Blocking Agents [PDF]
Pharmacology & Toxicology, 1994 Four neuromuscular blocking drugs, doxacurium, mivacurium, pipecuronium, and rocuronium have been or are about to be introduced into clinical practice. The purpose of this MiniReview is to describe their pharmacology, to consider their place in clinical anaesthetic practice, and to examine whether the needs of the clinican have been met.
openaire +3 more sources
Tetanus Toxin, a Neuromuscular Blocking Agent [PDF]
Nature, 1969 IN some cases of infectious tetanus a neuromuscular block with tetraplegia may follow the state of muscle spasms. We suggested1 that this effect was caused by the tetanus toxin itself rather than to an after-effect of muscle relaxants or other drugs. This hypothesis, however, had to be verified by experiments with animals.
H. E. Kaeser, A. Saner
openaire +3 more sources
A Wearable Soft Actuator for Directional Tactile Stimulation: Design and Testing
Advanced Intelligent Systems, EarlyView.A wearable actuator able to produce directional tactile stimulation is obtained by embedding a planar shape memory spring in silicone matrix. The matrix is designed taking into account skin characteristics and leveraging its multifunctionality: it acts as a bias load, improves the thermal behavior of the spring and wearability.
Fabio Lazzari +6 more
wiley +1 more source
Design, Modeling, and Control of a Soft Robotic Diaphragm‐Assist Device in a Respiratory Simulator
Advanced Intelligent Systems, EarlyView.A soft robotic diaphragm‐assist device using fabric‐based pneumatic actuators with a 2‐step control system to optimize synchronization and support is introduced. This system can detect the initiation of breathing to trigger assistance and regulate pressures to provide the correct level of inhalation augmentation. Validation and testing are completed on
Diego Quevedo‐Moreno +5 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Uniparental disomy (UPD) is a rare phenomenon in which both copies of a chromosome are inherited from a single parent. This can lead to genomic imprinting disorders and recessive disorders due to the presence of recessive pathogenic variants in both alleles. Additionally, depending on the mechanisms by which UPD occurs, mosaic aneuploidies may
Marta Carreño‐Hidalgo +4 more
wiley +1 more source
The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Advanced NanoBiomed Research, EarlyView.Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He +11 more
wiley +1 more source
Second messenger systems underlying amine and peptide actions on cardiac muscle in the horseshoe crab, Limulus polyphemus [PDF]
, 1989 The biochemical mechanisms by which octopamine, catecholamines and the peptide proctolin exert their actions on Limulus cardiac muscle were investigated.
Groome, J. R., Watson, Winsor H., III
core +2 more sources
The Role of rescue therapies in the treatment of severe ARDS [PDF]
, 2018 ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao +14 more
wiley +1 more source