Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki +3 more
doaj +1 more source
Preventing Isolated Perioperative Reintubation: Who is at highest risk? [PDF]
Objectives: 1. We aim to characterize IPR nationally through a retrospective review of the National Surgical Quality Improvement Program participant user file (NSQIP PUF).
Bauer, MD, Tyler M. +5 more
core +1 more source
Depth of anesthesia control using internal model control techniques [PDF]
The major difficulty in the design of closed-loop control during anaesthesia is the inherent patient variability due to differences in demographic and drug tolerance.
Anna, Shahab, Wen, Peng
core +2 more sources
A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J +17 more
core +2 more sources
Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul +6 more
core +2 more sources
Effect of pneumoperitoneum on the recovery from intense neuromuscular blockade by rocuronium in healthy patients undergoing laparoscopic surgery [PDF]
BackgroundThis study investigated the effect of pneumoperitoneum on the recovery from intense neuromuscular blockade by rocuronium in healthy patients undergoing laparoscopic abdominal surgery.MethodsThirty adult patients undergoing laparoscopic ...
Hong Soon Kim +4 more
doaj +1 more source
Identification of presynaptic neurotoxin complexes in the venoms of three Australian copperheads (Austrelaps spp.) and the efficacy of tiger snake antivenom to prevent or reverse neurotoxicity [PDF]
The venom of the Australian lowlands copperhead, Austrelaps superbus, produces significant and potentially lethal neurotoxic paralysis in cases of clinical envenomation. However, little is known about the neurotoxic components within this venom or venoms
Marcon, F, Nicholson, GM
core +1 more source
Sugammadex versus neostigmine in pediatric patients: a prospective randomized study
Background and objectives: Acetylcholinesterase inhibitors may cause postoperative residual curarization when they are used for reversal of neuromuscular blockade. Sugammadex reverses neuromuscular blockade by chemical encapsulation and is not associated
Turhan Kara +7 more
doaj +1 more source
Sugammadex - A short review and clinical recommendations for the cardiac anesthesiologist
This review outlines the basic pharmacodynamic and pharmacokinetic properties of sugammadex for the cardiac anesthesiologist. It describes the different clinical scenarios when sugammadex can be used during cardiac surgery and gives clinical ...
Hemmerling Thomas +3 more
doaj
Multiple model adaptive control of neuromuscular blockade: Design guidelines and clinical cases [PDF]
The high level of uncertainty of the dynamic response of patients subject to anaesthesia motivates the use of adaptive control methods. This paper proposes an approach based on Switched Multiple Model Adaptive Control (SMMAC) to tackle this problem in ...
Hugo Magalhães +4 more
core +1 more source

