Revista Brasileira de Anestesiologia, 2005 JUSTIFICATIVA E OBJETIVOS: Uma das mais importantes propriedades dos bloqueadores neuromusculares é o rápido início de ação, possibilitando intubação traqueal precoce. A administração de pequena dose de bloqueador não-despolarizante antes da dose plena é
José Carlos Canga +7 more
doaj +3 more sources
Bis- and Mixed-Tetrahydroisoquinolinium Chlorofumarates: New Ultra-Short-Acting Nondepolarizing Neuromuscular Blockers [PDF]
Journal of Medicinal Chemistry, 1999 Introduction. Neuromuscular blocking agents (NMBs)1 are used as adjuncts to anesthesia to provide skeletal muscle relaxation during surgery and to facilitate tracheal intubation. Emergency tracheal intubation maneuvers are routinely accomplished with the ultrashort-acting2 depolarizing NMB succinylcholine (suxamethonium).3 Although still widely used ...
, Boros +11 more
semanticscholar +5 more sources
Anesthesia & Analgesia, 2000 Molecular cloning and sequence comparison indicates a high degree of structural homology between muscle nicotinic acetylcholine (nACh) and serotonin-type 3 (5-HT(3A)) receptors, both members of the direct ligand-gated family of ion channels. Because of the structural similarities and common evolutionary origin of these receptors, neuromuscular blockers
K T, Min, C L, Wu, J, Yang
openaire +4 more sources
Anesthesia & Analgesia, 1996 Patients with type 1 neurofibromatosis (NF-1) have been reported to have prolonged responses to nondepolarizing (ND) neuromuscular blockers (NMBs). Responses to succinylcholine (SCh) have been described as increased, decreased, or normal. The purpose of this study was to assess responses to NMBs in NF-1 patients in order to determine the clinical ...
M G, Richardson, G K, Setty, S A, Rawoof
openaire +3 more sources
Possible recurrence of neuromuscular block following balloon dilation for bronchial stenosis in a young patient after bilateral lung transplantation: A case report. [PDF]
Medicine (Baltimore)Rationale: Sugammadex is a synthetic cyclodextrin derivative that reverses the effects of nondepolarizing neuromuscular blockers through selective encapsulation.
Ishihara T, Ito N, Uchida K.
europepmc +2 more sources
Anesthesia & Analgesia, 2005 We investigated the effects of early and late sepsis on the actions of nondepolarizing neuromuscular blockers by using a rat sepsis model induced by cecal ligation and puncture. Isometric twitch tensions of nerve-hemidiaphragm preparations elicited by indirect (phrenic nerve) supramaximal stimulation at 0.1 Hz were evaluated.
Eichi, Narimatsu +3 more
openaire +3 more sources
Influência da lidocaína no bloqueio neuromuscular produzido pelo rocurônio: estudo em preparação nervo frênico-diafragma de rato Influencia de la lidocaína en el bloqueo neuromuscular producido por el rocuronio: estudio en preparación nervio frénico-diafragma de ratón Influence of lidocaine on the neuromuscular block produced by rocuronium: study in rat phrenic-diaphragmatic nerve preparation [PDF]
Revista Brasileira de Anestesiologia, 2006 JUSTIFICATIVA E OBJETIVOS: O mecanismo de ação dos anestésicos locais (AL) na junção neuromuscular motivou a realização de vários estudos. Em baixas doses eles não interferem na transmissão neuromuscular, mas em altas doses podem comprometer a ...
Yolanda Christina S. Loyola +5 more
doaj +3 more sources
Anesthesiology, 2006 Background Sepsis attenuates the muscle-relaxing effects of nondepolarizing neuromuscular blockers. The authors investigated the effects of acute late sepsis on neuromuscular transmission and neuromuscular actions of rocuronium to clarify the mechanisms by which sepsis attenuates the effects of nondepolarizing neuromuscular ...
Tomohisa, Niiya +2 more
openaire +3 more sources
A Normal Distribution Model for the Pharmacodynamics of Nondepolarizing Neuromuscular Blockers [PDF]
Anaesthesia and Intensive Care, 1997 T A, Torda, G G, Graham, N R, Warwick
openaire +3 more sources
Magnesium Sulfate and Its Versatility in Anesthesia: A Comprehensive Review. [PDF]
CureusIn the field of general anesthesia, magnesium sulfate (MgSO4) has become a valuable adjunct because it provides a range of benefits that enhance and optimize conventional aesthetic procedures.
Dahake JS, Verma N, Bawiskar D.
europepmc +2 more sources