Results 121 to 130 of about 18,575 (296)

Single‐Cell Transcriptomic Analysis Reveals Epithelial‐Mesenchymal Transition and Key Gene AGRN as a Universal Programme in Gastrointestinal Tumours by an Artificial Intelligence‐Derived Prognostic Index

Med Research, EarlyView.
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni, Pengyuan Zhu, Liming Liu, Haiyang Wang, Jinzhe Zhou, Xianqing Wang, Song Wang, Liangchen Zhu, Songze Zhang, Yongxin Zhou, Bujun Ge, Qi Huang, Chenshen Huang   +12 more
wiley   +1 more source

Sugammadex or Neostigmine for prevention of post-operative pulmonary complications after major abdominal or thoracic surgery: study protocol for the SINFONIA (Sugammadex for preventioN oF pOst-operative pulmonary complIcAtions) randomised controlled superiority trial

Trials
Background Post-operative pulmonary complications (PPCs) are an important source of morbidity and mortality after major abdominal and thoracic surgery.
Jonathan A. Silversides, Louise Savic, Louise Hiller, Amy Hopkins, Katie Booth, Jennifer Dorey, Richard Smithson, James Mason, Samuel Frempong, Christina May, Ramani Moonesinghe, Ciara M. O’Donnell, Benedict Creagh-Brown, Rebecca Kandiyali, Joyce Yeung, Rupert Pearse, for the SINFONIA investigators   +16 more
doaj   +1 more source

Factors Associated with the Underuse of Sedatives and Neuromuscular Blocking Agents for Pediatric Emergency Endotracheal Intubation in Korea. [PDF]

Yonsei Med J, 2022
Lee JY, Lee SU, Son MH, Park JW, Jung JY, Kim JH.   +5 more
europepmc   +1 more source

Liver Steatosis in Induced Hepatocytes From Carriers of Spinal Muscular Atrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Although classically characterized as a motor neuron disease, spinal muscular atrophy (SMA) is increasingly recognized as a multisystem disorder. We previously showed hepatocyte‐intrinsic steatosis in SMA, raising the question of whether SMA carriers, who are typically asymptomatic, may also exhibit subclinical hepatic ...
Lingyu Sun, Damien Meng Kiat Leow, Loo Chien Wang, Michelle Yating Eio, Hiromi W. L. Koh, Zi Jian Khong, Gunaseelan Narayanan, Aloysius Kai Soon Teo, Richard Giadone, Radoslaw M. Sobota, Shi Yan Ng, Adrian Kee Keong Teo, Wei Yi Ong, Lee L. Rubin, Basil T. Darras, Crystal J. J. Yeo   +15 more
wiley   +1 more source

Neuromuscular blocking agents and opioids are major risk factors for developing pressure injuries in patients in the intensive care unit. [PDF]

Korean J Intern Med, 2022
Lee SY, Oh DK, Hong SB, Lim CM, Huh JW.
europepmc   +1 more source

Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]

, 1976
R. I. G. Hughes, J. P. Payne, N Sugai
openalex   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

The dose response effect of long-acting nondepolarizing neuromuscular blocking agents in children [PDF]

, 1984
Nishan G. Goudsouzian, Jeevendra J. A. Martyn, Letty M. P. Liu, Hassan H. Ali   +3 more
openalex   +1 more source

Epidemiology, Morbidity and Mortality Associated With Anesthesia in Early Life: A Subgroup Analysis of the German NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) Cohort

Pediatric Anesthesia, EarlyView.
ABSTRACT Background The NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) study, led by the ESAIC Clinical Trials Network, collected prospective data on 5609 children up to 60 weeks postmenstrual age undergoing 6542 anesthetic procedures across 165 centers in 31 European countries (ESAIC_CTN_NECTARINE).
Claudia Neumann, Alina Schenk, Ehrenfried Schindler, Karin Becke‐Jakob, German Nectarine Group Collaborators   +4 more
wiley   +1 more source