Results 101 to 110 of about 36,545 (280)

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Comparison of 3 Rates for the Continuous Infusion of Mivacurium During Ambulatory Vitreoretinal Surgery Under General Anesthesia: A Prospective, Randomized, Controlled Clinical Trial

Drug Design, Development and Therapy, 2022
Yi Zhang,1,* Chunhua Xi,1,* Jianying Yue,1 Mengmeng Zhao,2 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Operation Center, Beijing Tongren Hospital, Capital ...
Zhang Y, Xi C, Yue J, Zhao M, Wang G
doaj  

Sugammadex, a neuromuscular blockade reversal agent, causes neuronal apoptosis in primary cultures. [PDF]

, 2013
Sugammadex, a γ-cyclodextrin that encapsulates selectively steroidal neuromuscular blocking agents, such as rocuronium or vecuronium, has changed the face of clinical neuromuscular pharmacology.
Aguirre Rueda, Diana, Aldasoro Celaya, Martín, García, Alma, Gil Bisquert, Anna, Granell Gil, Manuel, Iradi Casal, Antonio, Mauricio Aviñó, María Dolores, Obrador, Elena, Palanca Sanfrancisco, José María, Vallés Martí, Lilián Soraya, Vila Salinas, José María   +10 more
core   +2 more sources

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Efek Pemberian Magnesium Sulfat 45 Mg/kgBB terhadap Kualitas Tindakan Intubasi Endotrakeal Tanpa Obat Pelumpuh Otot dan Perubahan Respons Hemodinamik

Jurnal Anestesi Perioperatif, 2019
Intubasi endotrakeal merupakan tindakan berisiko tinggi yang menghasilkan stimulasi adrenergik. Intubasi endotrakeal menggunakan obat pelumpuh otot sebagai standar baku dapat menimbulkan efek samping berupa reaksi anafilaksis dan rekurisasi pascabedah ...
Fatima Fatima, Erwin Pradian, Dedi Fitri Yadi   +2 more
doaj   +1 more source

The construction and evaluation of a device for mechanomyography in anaesthetized Göttingen minipigs [PDF]

, 2013
OBJECTIVE: To devise a method for assessing evoked muscle strength on nerve stimulation [mechanomyography (MMG)] in the anaesthetized minipig. STUDY DESIGN: Prospective observational. ANIMALS: Sixty male Göttingen minipigs weighing 10.5–26.0 kg. METHODS:
Adrian Thompson, Ali, Clutton, Clutton, Dahaba, Engbaek, Fuchs-Buder, Harper, Holly Lawson, Hopkins, Keith Simpson, Kopman, Kopman, Kosala Dissanayake, Krarup, Loan, Maddineni, Martin-Flores, McCoy, McGrath, Michael Eddleston, R. Eddie Clutton, Richards, Ritchie, Viby-Mogensen   +24 more
core   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Neuromuscular Monitoring, Muscle Relaxant Use, and Reversal at a Tertiary Teaching Hospital 2.5 Years after Introduction of Sugammadex: Changes in Opinions and Clinical Practice

Anesthesiology Research and Practice, 2015
Sugammadex was introduced to Royal Perth Hospital in early 2011 without access restriction. Two departmental audits (26-page online survey and 1-week in-theatre snapshot audit) were undertaken to investigate the change of beliefs and clinical practice ...
Thomas Ledowski, Jing Shen Ong, Tom Flett   +2 more
doaj   +1 more source

Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study [PDF]

, 2010
INTRODUCTION: Non-excitable muscle membrane indicates critical illness myopathy (CIM) during early critical illness. We investigated predisposing risk factors for non-excitable muscle membrane at onset of critical illness.
Claudia D Spies, Didier Keh, Florian Bubser, Joachim Spranger, Klaus D Wernecke, Maria Deja, Simone Spuler, Steffen Weber-Carstens, Susanne Koch   +8 more
core   +3 more sources

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source