Results 81 to 90 of about 19,227 (236)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Investigation of the Protective Effect of Morin on Oxidative Stress and Apoptosis in Malathion‐Induced Hepatotoxicity in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Malathion (MAL) is a widely used organophosphate pesticide associated with hepatotoxicity through oxidative stress and apoptosis. Morin, a naturally occurring flavonoid, exhibits potent antioxidant and anti‐inflammatory properties. This study investigated oxidative stress, inflammatory, and apoptotic alterations induced by acute and subacute ...
Seval Yılmaz, Eda İ. Demirbağ, Hakan Bağ, Ali O. Çeribaşı   +3 more
wiley   +1 more source

The Effects of Metoclopramide Premedication on the Neuromuscular Blockade of Vecuronium and Mivacurium

Cerrahpaşa Medical Journal, 2014
Elimination of metoclopramide is mostly made by cholinesterase enzyme. Especially cholinesterase enzyme took place at the cessation of the effects of depolarisating neuromuscular blocking agents.
Hüsamettin KEŞKÜŞ, Ziya SALİHOĞLU
doaj  

Neuromuscular Monitoring, Muscle Relaxant Use, and Reversal at a Tertiary Teaching Hospital 2.5 Years after Introduction of Sugammadex: Changes in Opinions and Clinical Practice

Anesthesiology Research and Practice, 2015
Sugammadex was introduced to Royal Perth Hospital in early 2011 without access restriction. Two departmental audits (26-page online survey and 1-week in-theatre snapshot audit) were undertaken to investigate the change of beliefs and clinical practice ...
Thomas Ledowski, Jing Shen Ong, Tom Flett   +2 more
doaj   +1 more source

Route‐Dependent Toxicity and Ecological Selectivity of Melaleuca alternifolia Essential Oil in Apis mellifera Linnaeus, 1758 (Hymenoptera: Apidae)

Environmental Toxicology, EarlyView.
ABSTRACT The intensification of agricultural practices has led to an increase in the use of insecticides, raising concerns about the exposure of non‐target organisms, particularly pollinators. In this context, plant‐derived essential oils have been proposed as environmentally friendlier alternatives due to their low persistence; however, their ...
Silvane Zancanaro de Oliveira, Elizabete Artus Berte, Juliana Marceli Hofma Lopes, Cristiane Lurdes Paloschi, Edgar de Souza Vismara, Vitória Alves Pereira, Fernanda Raulino Domanski, Natália Ramos Mertz, Fabiana Martins Costa, Everton Ricardi da Silva Lozano, Jhenneffer Tainara Zancanaro Ghizzi, Michele Potrich   +11 more
wiley   +1 more source

Neuromuscular blocking agents and intubation [PDF]

Anaesthesia, 2018
M, Sorbello, S, Falcetta, I, Di Giacinto, R, Cataldo   +3 more
openaire   +2 more sources

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Neuromuscular Blocking Agents and Reversal Agents Usage, and Neuromuscular Blockade Monitoring in the Intensive Care Unit – Review Article

International Journal of General Medicine
Maciej Szewczyk,1 Aleksandra Bieniecka,2 Kamil Sobolewski,3,4 Łukasz Banasiak,5 Łukasz Grabarczyk6 1Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology with the Department of ...
Szewczyk M, Bieniecka A, Sobolewski K, Banasiak Ł, Grabarczyk Ł   +4 more
doaj  

Peri‐operative management of patients having day surgery: a consensus statement from the Association of Anaesthetists, British Association for Day Surgery and the Association of Paediatric Anaesthetists, Great Britain and Ireland

Anaesthesia, EarlyView.
Summary Introduction Day surgery is now recognised widely as being a vital component of modern healthcare delivery with overall day surgery rates in the UK now > 85%. Day surgery offers an enhanced experience for patients with reduced risk of postoperative complications (e.g.
Craig R. Bailey, David Bunting, Lindsay Hudman, Shivan Kanani, Kirstin May, Catalina Stendall, Rachel Tibble, Allan Xu, Matthew D. Wiles   +8 more
wiley   +1 more source