Results 61 to 70 of about 19,469 (260)

Anesthesia Management for Evacuation of Cerebral Abscess in Geriatric Patient with Myasthenia Gravis

Jurnal Neuroanestesi Indonesia
A Cerebral abscess is an intracranial focal abscess which is a life-threatening emergency. Myasthenia gravis is an autoimmune disorder caused by antibodies targeting the neuromuscular junction’s post-synaptic receptor.
I Putu Pramana Suarjaya, Osmond Purwanto, Kristian Felix Wundiawan, Ida Bagus Krisna Jaya Suatawan   +3 more
doaj   +1 more source

Occurrence of butyrylcholinesterase polymorphisms in patients undergoing surgery in Slovakia [PDF]

Caspian Journal of Internal Medicine, 2023
Background: Post-operative residual curarization is a persisting problem, characterized by muscle fatigue, exhaustion or paresis, caused by the use of neuromuscular blocking agents with prolonged postoperative effect.
Lukáš Čuchráč, Marta Mydlárová Blaščáková, Jozef Firment, Jana Šimonová, Jarmila Bernasovská, Janka Vašková   +5 more
doaj  

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

MONITORING OF VARIOUS TYPES OF NEUROMUSCULAR BLOCKADE

Вестник анестезиологии и реаниматологии, 2018
Goal of the review: to build up the current understanding of electrophysiological specific features of various neuromuscular blockades. Having analyzed the results of multiple studies devoted to investigation of the impact of various medications ...
N. V. Chubchenko, K. M. Lebedinskiy
doaj   +1 more source

Good Clinical Research Practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents

, 1996
Based on an international consensus conference held in Copenhagen in the autumn of 1994, a set of guidelines for Good Clinical Research Practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents are presented. The guidelines are intended
Engbæk, J., Jensen, F. S., L. Gramstad, Jensen, E., Koscielniak-Nielsen, Z., L. I. Eriksson, F. S. Jensen, J. Engbæk, Viby-Mogensen, J., Z. Koscielniak‐Nielsen, Skovgaard, L. T., Østergaard, D., J. Viby‐Mogensen, L. T. Skovgaard, Gramstad, L., E. Jensen, D. ØStergaard, Eriksson, L. I.   +17 more
core   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Neuromuscular-blocking agents for tracheal intubation in pediatric patients (0-12 years): A systematic review and meta-analysis

, 2020
: Background The benefit of using neuromuscular-blocking agents to facilitate tracheal intubation in pediatric patients remains unclear due to variations in design, treatments, and results among trials.
Saldien, V., Berghmans, J., Vanlinthout, Luc E., Hens, Niel, Raphaël Lapré, Uwimpuhwe, Germaine, Driessen, Jacques J., Lapré, R., Luc E. Vanlinthout, Vanlinthout, L.E., Saldien, Vera, Uwimpuhwe, G., Lapr, R, Berghmans, Johan, Driessen, J.J., Johan Berghmans, Geniets, B, Vanlinthout, LE, Hens, N, Saldien, V, Lapre, Raphael, Geniets, B., Geniets, Benedicte, Uwimpuhwe, G, Bénédicte Geniets, Vera Saldien, Germaine Uwimpuhwe, Driessen, JJAG, Jacques J. Driessen, Niel Hens, Hens, N.   +30 more
core   +1 more source