Results 41 to 50 of about 18,093 (237)

Effects of avoiding neuromuscular blocking agents during maintenance of anaesthesia on recovery characteristics in patients undergoing craniotomy for supratentorial lesions: A randomised controlled study

Indian Journal of Anaesthesia, 2017
Background and Aims: Neuromuscular blocking agents have been one of the cornerstones of anaesthesia. With the advent of newer surgical, anaesthetic and neurological monitoring techniques, their utility in neuroanaesthesia practice seems dispensable.
Ruchi A Jain, Anita N Shetty, Shrikanta P Oak, Anjana S Wajekar, Madhu B Garasia   +4 more
doaj   +1 more source

Chromatin Packing Domain Engineering Through the Manipulation of Nuclear Cationic States

Advanced Science, EarlyView.
Manipulation of intranuclear divalent cation concentrations rapidly and reversibly remodels chromatin packing domains in living cells. Magnesium depletion disrupts domain compaction, heterochromatin organization, and transcriptional regulation, whereas magnesium loading promotes more compact and stable domains.
Cody L. Dunton, Carrillo Paola Gonzalez, Luay Almassalha, Wing Shun Li, Ruyi Gong, Nicolas Acosta, I Chae Ye, Jane Frederick, Christopher Hogg, Saira John, J. A. Gareth Williams, Rikkert J. Nap, Igal Szleifer, Vadim Backman   +13 more
wiley   +1 more source

Neuromuscular Blocking Agents

Journal of Pharmacy and Pharmacology, 1959
Abstract NSN- and NNN-Tris-onium compounds related to dihexasulphonium and dihexazonium in which N-alkyl substituents are varied have been synthesised. All compounds tested qualitatively resembled tubocurarine in their action. Stepwise replacement of Et by Me in dihexasulphonium tri-ethiodide decreases potency and some C 10-like effects ...
Fiona Macleod Carey, D Edwards, J J Lewis, J B Stenlake   +3 more
openaire   +1 more source

Engineering Antibodies into Targeted Chimeras: From Recognition Modules to Programmable Degraders

Advanced Science, EarlyView.
Antibody can be engineered into diverse lysosome‐targeting chimeras that convert target recognition into active degradation. By coupling antibody binding with recruited receptors, encoded domains, conjugated ligands, or nanoparticle scaffolds, these antibody‐associated targeted chimeras (AbTACs) platforms direct extracellular and membrane proteins ...
Kaige Chen, Quanyin Hu
wiley   +1 more source

Respiratory muscle activity after spontaneous, neostigmine- or sugammadex-enhanced recovery of neuromuscular blockade: a double blind prospective randomized controlled trial

BMC Anesthesiology, 2019
Background The use of neostigmine after neuromuscular blockade (NMB) has been associated with postoperative respiratory complications. In previous studies, we found lower diaphragmatic activity after neostigmine reversal of NMB, compared to sugammadex ...
Tom Schepens, Koen Janssens, Sabine Maes, Davina Wildemeersch, Jurryt Vellinga, Philippe G. Jorens, Vera Saldien   +6 more
doaj   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu, Monther AlSiyabi, Aida Ebrahimi   +2 more
wiley   +1 more source

Sugammadex: Breaking Through Residual Paralysis after Neostigmine’s Limits [PDF]

Journal of Clinical and Diagnostic Research
Persistent neuromuscular blockade following the use of Neuromuscular Blocking Agents (NMBAs) remains a significant postoperative concern, often resulting in delayed recovery and prolonged stays in the Post- Anaesthesia Care Unit (PACU).
Aparna Bagle, Sania Rodrigues
doaj   +1 more source

Intravenous infusion of rocuronium bromide prolongs emergence from propofol anesthesia in rats.

PLoS ONE, 2021
BackgroundNeuromuscular blocking agents induce muscle paralysis via the prevention of synaptic transmission at the neuromuscular junction and may have additional effects at other sites of action. With regard to potential effects of neuromuscular blocking
Kaoru Suzuki, Hiroshi Sunaga, Kentaro Yamakawa, Yoshifumi Suga, Ichiro Kondo, Tsunehisa Tsubokawa, Shoichi Uezono   +6 more
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Effects of neuromuscular blocking agents on central respiratory chemosensitivity in newborn rats

Biological Research, 2005
Neuromuscular blocking agents suppress central respiratory activity through their inhibitory effects on preinspiratory neurons and the synaptic drive from preinspiratory neurons to inspiratory neurons.
SHIGEKI SAKURABA, SHUN-ICHI KUWANA, LARS I ERIKSSON, YASUMASA OKADA, RYOICHI OCHIAI, MASANORI KASHIWAGI, EIKI HATORI, STEN G. E. LINDAHL, JUNZO TAKEDA   +8 more
doaj