Results 171 to 180 of about 18,093 (237)

Management of Neuromuscular Blocking Agents in Critically Ill Patients with Lung Diseases. [PDF]

J Clin Med
Iavarone IG, Al-Husinat L, Vélez-Páez JL, Robba C, Silva PL, Rocco PRM, Battaglini D.   +6 more
europepmc   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Early neuromuscular blocking agents for adults with acute respiratory distress syndrome: a systematic review, meta-analysis and meta-regression. [PDF]

BMJ Open, 2020
Shao S, Kang H, Tong Z.
europepmc   +1 more source

Microtubules in Spinal Cord Injury: From Cytoskeletal Dysregulation to Therapeutic Regeneration

Journal of Neurochemistry, Volume 170, Issue 8, August 2026.
Graphical illustration of the microtubule interactome following spinal cord injury as potential targets for therapy. ABSTRACT Spinal cord injury (SCI) triggers an immediate and sustained disruption of the composition and organization of the neuronal cytoskeleton.
Itzhak Fischer, Peter W. Baas
wiley   +1 more source

Adeno‐Associated Virus Gene Therapy for Spinal Muscular Atrophy Induces Hepatotoxicity via Cytokine and Macrophage Activation

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Hepatotoxicity is a common and significant adverse effect associated with adeno‐associated virus (AAV) gene therapy; however, the underlying mechanisms remain unknown. In this study, we demonstrated innate immune activation in two patients with spinal muscular atrophy shortly after receiving AAV9 gene therapy with onasemnogene abeparvovec ...
Aiko Sakai, Masaya Sugiyama, Masafumi Onodera, Fujiko Fukushima, Mai Tanaka, Toru Uchiyama, Masashi Mizokami, Ryo Sumazaki   +7 more
wiley   +1 more source

Impairments in mitochondrial dynamics and morphology in skeletal muscle of breast cancer patients after a single paclitaxel administration

Experimental Physiology, Volume 111, Issue 8, Page 3502-3513, 1 August 2026.
Abstract Standard chemotherapy regimens for patients with breast cancer are based on epirubicin–cyclophosphamide (EC) and paclitaxel (TAX) administrations. While it has been shown that first EC administration impairs mitochondrial homeostasis, the isolated effects of TAX have not been studied without previous chemotherapy exposure.
Joris Mallard, Elyse Hucteau, Laura Somme, Hervé Bischoff, Valérie Demais, Pauline Silvestrin, Anne‐Laure Charles, Roland Schott, Xavier Pivot, Thomas J. Hureau, Allan F. Pagano   +10 more
wiley   +1 more source

Neuromuscular blocking agents in acute respiratory distress syndrome: updated systematic review and meta-analysis of randomized trials. [PDF]

Intensive Care Med Exp, 2020
Tarazan N, Alshehri M, Sharif S, Al Duhailib Z, Møller MH, Belley-Cote E, Alshahrani M, Centofanti J, McIntyre L, Baw B, Meade M, Alhazzani W, GUIDE Group.   +12 more
europepmc   +1 more source

Divergent skeletal muscle metabolite exchange in insulin‐like growth factor‐1‐stimulated myotubes and resistance‐exercised human muscle

Experimental Physiology, Volume 111, Issue 8, Page 3784-3799, 1 August 2026.
Abstract Skeletal muscle hypertrophy requires a substantial nutrient influx for biomass accretion, but global metabolite exchange during growth is poorly characterized. Therefore, we profiled the metabolite uptake and release in insulin‐like growth factor‐1 (IGF‐1)‐stimulated C2C12 myotubes and human muscle 24 h after resistance exercise ...
Tim Havers, Moritz Eggelbusch, Marius Meinhold, Kira Sing, Rainer Okrojek, Anna Artati, Michael Witting, Dominik Lutter, Claire V. Kieker, Collin Starke, Tushar More, Karsten Hiller, Flemming Dela, Martin Schönfelder, André Kafka, Stephan Geisler, Henning Wackerhage   +16 more
wiley   +1 more source

Centriolar Protein POC5 Regulates Human Adipogenesis and Cellular Senescence: Insights From a Novel Metabolic Ciliopathy

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
The identification of a patient carrying a novel homozygous p.(Gln206Ter) POC5 variant revealed a metabolic phenotype associated with POC5 deficiency. POC5 deficiency disrupts centriolar architecture and ciliary organization, leading to impaired proliferation, premature cellular senescence, and reduced insulin signaling.
Valeria Pistorio, Camille Vatier, Émilie Capel, Carine Beaupère, Martine Auclair, Virginie Steunou, Romain Morichon, Michael Joubert, Corinne Vigouroux, Jérémie Gautheron, Isabelle Jéru   +10 more
wiley   +1 more source