Results 21 to 30 of about 17,482 (208)

Compared efficacy and tolerance of the neuromuscular blockade induced by brand-name (Nimbex®) and generic (Cisatrex®) of cisatracurium in mechanically ventilated critically ill patients: a crossover double-blind randomized study

The Pan African Medical Journal, 2020
INTRODUCTION: Use of generic drugs is common. However, there is still concern among patients and physicians that brand name drugs are more efficient. The aim of the study was to compare efficacy and tolerance between two forms of cisatracurium: brand ...
Nesrine Fraj, Khaoula Meddeb, Abdelbaki Azouzi, Sana Romdhani, Helmi Ben Saad, Mohamed Boussarsar   +5 more
doaj   +1 more source

Anesthetic management of a child with phosphomannomutase-2 congenital disorder of glycosylation (PMM2-CDG)

JA Clinical Reports, 2017
Background Glycosylation is one of the major posttranslational modifications of proteins and it is essential for proteins to obtain normal biological functions.
Wataru Sakai, Yusuke Yoshikawa, Yasuyuki Tokinaga, Michiaki Yamakage   +3 more
doaj   +1 more source

Neuromuscular Blocking Agents

Journal of Pharmacy and Pharmacology, 1958
Abstract The preparation of two further NSN-tris-ethonium compounds, 9-ethyl-9-thioniaheptadecylenebis(triethylammonium) triiodide (dioctasulphonium triethiodide; DOSE) and 11-ethyl-11-thioniaheneicosylenebis(triethylammonium) triiodide (didecasulphonium triethiodide; DDSE) is described.
D Edwards, J J Lewis, J B Stenlake, M S Zoha   +3 more
openaire   +2 more sources

Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions

Anesthesia Research
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj   +1 more source

Intradermal skin tests for rocuronium and cisatracurium in patients with a history of allergy: a retrospective study [PDF]

Korean Journal of Anesthesiology, 2018
Background Neuromuscular blocking agents (NMBAs) are a leading cause of perioperative anaphylaxis. However, the performance of systematic screening skin tests to detect reactions for NMBAs prior to general anesthesia is not recommended.
Yu Yil Kim, Ik Thae Kim, Sung In Shin, So Mang Yim   +3 more
doaj   +1 more source

Tracheal Intubation through the I-gel for Emergency Cesarean Section in a Patient with Multidrug Hypersensitivity: A New Technique

Case Reports in Anesthesiology, 2014
31-year-old female with hypersensitivity to local anesthetics and neuromuscular blocking agents presented for emergency Cesarean section. We successfully performed I-gel-assisted tracheal intubation without using neuromuscular blockers.
Kartika Balaji Samala, Yuri Uchiyama, Yasuyuki Tokinaga, Yukitoshi Niiyama, Soshi Iwasaki, Michiaki Yamakage   +5 more
doaj   +1 more source

ClC-1 Inhibition as a Mechanism for Accelerating Skeletal Muscle Recovery After Neuromuscular Block in Rats

Nature Communications
Neuromuscular blocking agents are used commonly to induce skeletal muscle relaxation during surgery. While muscle relaxation facilitates surgical procedures and tracheal intubation, adequate recovery of muscle function after surgery is required to ...
Marianne Skals, Martin Broch-Lips, Martin Brandhøj Skov, Anders Riisager, Judith Ceelen, Ole Bækgaard Nielsen, Sorin J. Brull, Hans D. de Boer, Thomas Holm Pedersen   +8 more
doaj   +1 more source

Comparison of the Effects of Sugammadex Recommended Dose (2 mg/kg) and Fixed Dose of 200 mg on the Reversal of Moderate Neuromuscular Block and Recovery Profile in Adult Patients

Medicina
Background and Objectives: Neuromuscular blocking agents are essential to ensure optimal surgical conditions during general anesthesia. Sugammadex, a selective binding agent, is widely used to reverse neuromuscular blockade.
Ji-Yoon Jung, Sung-Ae Cho, Woojin Kwon, Hongwook Kim, Tae-Yun Sung   +4 more
doaj   +1 more source

Anaphylactic reactions after cisatracurium administration in two patients -a report of two cases- [PDF]

Korean Journal of Anesthesiology, 2013
Cisatracurium was initially characterized to have no evident histamine-releasing potential with excellent cardiovascular stability. However, severe anaphylactic reactions to cisatracurium that resulted in bronchospasms and cardiovascular collapse have ...
Yangin Yoon, Byungdoo Lee, Hyung-Seok Seo, Jiyoun Bang, Seung Il Ha, Jun-Gol Song   +5 more
doaj   +1 more source

Neuromuscular Blocking Agents

Journal of Pharmacy and Pharmacology, 1959
Abstract NSN- and NNN-Tris-onium compounds related to dihexasulphonium and dihexazonium in which N-alkyl substituents are varied have been synthesised. All compounds tested qualitatively resembled tubocurarine in their action. Stepwise replacement of Et by Me in dihexasulphonium tri-ethiodide decreases potency and some C 10-like effects ...
Fiona Macleod Carey, D Edwards, J J Lewis, J B Stenlake   +3 more
openaire   +1 more source