Results 31 to 40 of about 16,696 (258)

Comparison of the Effects of Sugammadex Recommended Dose (2 mg/kg) and Fixed Dose of 200 mg on the Reversal of Moderate Neuromuscular Block and Recovery Profile in Adult Patients

Medicina
Background and Objectives: Neuromuscular blocking agents are essential to ensure optimal surgical conditions during general anesthesia. Sugammadex, a selective binding agent, is widely used to reverse neuromuscular blockade.
Ji-Yoon Jung, Sung-Ae Cho, Woojin Kwon, Hongwook Kim, Tae-Yun Sung   +4 more
doaj   +1 more source

Small doses of epinephrine prolong the recovery from a rocuronium-induced neuromuscular block: a case report

BMC Anesthesiology, 2018
Background During anaesthesia it is not uncommon to administer epinephrine in patients blocked by non-depolarizing muscle relaxants. However, there are few reports on possible interaction of epinephrine with neuromuscular transmission in humans.
Hubert J. Schmitt
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Embracing Complexity: Peptides as Tunable Scaffolds in the Construction of Discrete Supramolecular Systems

Angewandte Chemie, EarlyView.
The inherent chirality, tunability, biocompatibility, and robustness of peptides provide an exciting opportunity for supramolecular chemistry. In this mini‐review, we explore uses of peptides in discrete supramolecular systems, how chemists can draw inspiration from larger biological assemblies, and discuss how embracing the complexity of peptide ...
Ben E. Barber, Ellen M. G. Jamieson, Leah E. M. White, Charlie T. McTernan   +3 more
wiley   +2 more sources

Anaphylactic reactions after cisatracurium administration in two patients -a report of two cases- [PDF]

Korean Journal of Anesthesiology, 2013
Cisatracurium was initially characterized to have no evident histamine-releasing potential with excellent cardiovascular stability. However, severe anaphylactic reactions to cisatracurium that resulted in bronchospasms and cardiovascular collapse have ...
Yangin Yoon, Byungdoo Lee, Hyung-Seok Seo, Jiyoun Bang, Seung Il Ha, Jun-Gol Song   +5 more
doaj   +1 more source

Neuromuscular Blocking Agents

Journal of Pharmacy and Pharmacology, 1958
Abstract The preparation of two further NSN-tris-ethonium compounds, 9-ethyl-9-thioniaheptadecylenebis(triethylammonium) triiodide (dioctasulphonium triethiodide; DOSE) and 11-ethyl-11-thioniaheneicosylenebis(triethylammonium) triiodide (didecasulphonium triethiodide; DDSE) is described.
D Edwards, J J Lewis, J B Stenlake, M S Zoha   +3 more
openaire   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Effects of avoiding neuromuscular blocking agents during maintenance of anaesthesia on recovery characteristics in patients undergoing craniotomy for supratentorial lesions: A randomised controlled study

Indian Journal of Anaesthesia, 2017
Background and Aims: Neuromuscular blocking agents have been one of the cornerstones of anaesthesia. With the advent of newer surgical, anaesthetic and neurological monitoring techniques, their utility in neuroanaesthesia practice seems dispensable.
Ruchi A Jain, Anita N Shetty, Shrikanta P Oak, Anjana S Wajekar, Madhu B Garasia   +4 more
doaj   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Respiratory muscle activity after spontaneous, neostigmine- or sugammadex-enhanced recovery of neuromuscular blockade: a double blind prospective randomized controlled trial

BMC Anesthesiology, 2019
Background The use of neostigmine after neuromuscular blockade (NMB) has been associated with postoperative respiratory complications. In previous studies, we found lower diaphragmatic activity after neostigmine reversal of NMB, compared to sugammadex ...
Tom Schepens, Koen Janssens, Sabine Maes, Davina Wildemeersch, Jurryt Vellinga, Philippe G. Jorens, Vera Saldien   +6 more
doaj   +1 more source