Results 81 to 90 of about 1,597,608 (182)

Evaluation of the effects of a single bolus of cisatracurium as part of an anesthetic protocol in cats undergoing orthopedic surgery

open access: yesBMC Veterinary Research
Non-depolarizing neuromuscular blocking agents (NMBAs) are commonly used in human anesthesia but remain uncommon in veterinary medicine. This study evaluated the effects of 0.5 mg/kg cisatracurium IV on muscle relaxation, cardiovascular variables and ...
Claudia Interlandi   +7 more
doaj   +1 more source

Incidence of postoperative residual neuromuscular blockade: a prospective observational study

open access: yesColombian Journal of Anesthesiology
Introduction: The use of non-depolarizing neuromuscular blockers (ND-NMB) is essential in anesthetic management as it improves ventilation conditions, airway management, and surgical conditions.
Diego Luis Vélez-Agudelo   +3 more
doaj   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Probing Cinnamamides and Benzamides as Anthelmintics: Discovery of Potent Drug‐Like Agents Against Angiostrongylus cantonensis

open access: yesChemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Cynnamoyl benzylpiperazine was identified as drug‐like derivative of cinnarizine with anthelmintic activity against A. cantonensis. In this work, 15 out of 31 derivatives showed improved anthelmintic activity with increased solubility. A SAR study was carried out to determine the molecular features involved in such effect.
Bruna L. Lemes   +10 more
wiley   +1 more source

Interactions between suxamethonium and non-depolarizing neuromuscular blocking-drugs [PDF]

open access: yes, 1982
In anaesthetized cats, we have confirmed that previously injected suxamethonium potentiates non-depolarizing neuromuscular blocking drugs whereas, when injected during the block, suxamethonium antagonizes the paralysis. We have attempted to explain these
Law, LW   +171 more
core   +3 more sources

Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine [PDF]

open access: yes, 2013
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs   +14 more
core   +2 more sources

Aktuelni problemi u primeni mišićnih relaksanata u kliničkoj praksi [PDF]

open access: yesVojnosanitetski Pregled, 2003
Konstantinović Slavko, Balkanov Trajan
doaj   +1 more source

Comparative Study of Efficacy and Safety of Rocuronium Bromide with Suxamethonium Chloride for Tracheal Intubation

open access: yesNational Journal of Medical Research
Background: Tracheal intubation is a cornerstone of modern anesthetic practice, with neuromuscular blocking agents playing a critical role. Among these agents, Suxamethonium chloride is widely used for its quick onset and brief duration.
Asawari Wagh   +3 more
doaj   +1 more source

Neuromuscular blockade and reversal

open access: yes, 2017
Over the past 70 years since the introduction of d-tubocurarine, the search for an ideal neuromuscular blocking agent has led to the development of the depolarizing drug, succinylcholine (suxamethonium), with its rapid onset of action and plasma ...
Thomas Fuchs-Buder, Jennifer M. Hunter
core   +1 more source

Neuromuscular fatigability during repeated-sprint exercise in male athletes [PDF]

open access: yes, 2015
Purpose - To determine the pattern of neuromuscular fatigability that manifests during repeated sprint running exercise. Methods - Twelve male participants (mean ± SD age, 25 ± 6 yr; stature, 180 ± 7 cm; body mass, 77 ± 7 kg), currently training and ...
Thomas, Kevin   +3 more
core   +1 more source

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