Results 41 to 50 of about 1,597,608 (182)

Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1976
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was ...
R, Hughes, J P, Payne, N, Sugai
openaire   +2 more sources

THE NATURE OF ACETYLCHOLINE RECEPTOR [PDF]

open access: yesActa Medica Iranica, 1983
The present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. AChE molecules stand at the gate of this
M.E. TASHAYOD
doaj   +1 more source

Malignant hyperthermia – state of knowledge

open access: yesJournal of Education, Health and Sport, 2022
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke   +6 more
doaj   +1 more source

Anaesthetic management in a patient with multiple sclerosis

open access: yesIndian Journal of Anaesthesia, 2011
Multiple sclerosis (MS) is a rare autoimmune demyelinating disorder of the central nervous system clinically manifesting as periodic attacks of varied neurologic symptoms, eventually progressing to fixed neurologic deficits and disability.
Lata M Kulkarni   +3 more
doaj   +1 more source

A systematic review and meta-analysis of the use of succinylcholine to facilitate tracheal intubation in neonates

open access: yesAin Shams Journal of Anesthesiology, 2021
Use of succinylcholine in neonates is surrounded by many controversies. The need to review this topic stems from the fact that though there is an abundance of information, but there are divergent views regarding its use in neonates.
Bhavna Gupta, Priyanka Mishra
doaj   +1 more source

In-depth exploration of sugammadex and novel neuromuscular blockade antagonists: a narrative review

open access: yesFrontiers in Pharmacology
Sugammadex is a modified γ-cyclodextrin widely used in clinical practice to reverse neuromuscular blockade induced by non-depolarizing neuromuscular blockade agents, notably rocuronium and vecuronium.
Yingbei Qi   +5 more
doaj   +1 more source

Extreme Paralysis Following Rocuronium Administration in a Myasthenia Gravis Patient: A Case Report

open access: yesClinical Practice and Cases in Emergency Medicine, 2023
Introduction: The use of paralytics during rapid sequence intubation (RSI) in patients with myasthenia gravis (MG) remains a controversial topic in emergency medicine.
Kelsey Billups   +2 more
doaj   +1 more source

Optimizing Organ Donation After Euthanasia: A Critical Appraisal

open access: yesTransplantology
This Critical Appraisal aims to explore the pharmacokinetics and pharmacodynamics of medications used in organ donors after euthanasia (ODE) and their impact on abdominal organ quality.
E. A. J. Alkemade   +6 more
doaj   +1 more source

EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON THE CARDIAC VAGUS NERVE IN THE GUINEAPIG

open access: yesBritish Journal of Anaesthesia, 1980
The ability of gallamine, metocurine, pancuronium, tubocurarine and atropine to block the response to postganglionic stimulation of the vagus nerve were measured in isolated, spontaneously beating guineapig atria. From analysis of the results in conjunction with those of earlier assays of concentrations that block effects of preganglionic vagal ...
S L, Son, D R, Waud
openaire   +2 more sources

Identification and Quantitation of Six Non-Depolarizing Neuromuscular Blocking Agents by LC-MS in Biological Fluids [PDF]

open access: yesJournal of Analytical Toxicology, 2004
A liquid chromatography-electrospray-mass spectrometry technique for the screening and determination of five non-depolarizing neuromuscular blocking agents (NDBAs), atracurium and its product of degradation/metabolite laudanosine, rocuronium, pancuronium, vecuronium, and mivacurium has been developed using ambenonium as the internal standard (I.S ...
Hervé, Sayer   +5 more
openaire   +2 more sources

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