Results 21 to 30 of about 3,371 (156)

Preparing for the unexpected: special considerations and complications after sugammadex administration

open access: yesBMC Anesthesiology, 2017
Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki   +3 more
doaj   +1 more source

INFLUENCE OF “PRIMING” ON THE POTENCY OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS

open access: yesBritish Journal of Anaesthesia, 1987
Dose-response curves have been constructed to determine the ED50 and ED95 (doses required to produce a 50% and a 95% block, respectively) following administration of a small "priming" dose of atracurium 50 micrograms kg-1, vecuronium 10 micrograms kg-1 or pancuronium 10 micrograms kg-1.
M M, Brady, R K, Mirakhur, F M, Gibson
openaire   +2 more sources

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

open access: yesFrontiers in Pharmacology, 2023
Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji   +17 more
doaj   +1 more source

Malignant hyperthermia – state of knowledge

open access: yesJournal of Education, Health and Sport, 2022
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke   +6 more
doaj   +1 more source

A systematic review and meta-analysis of the use of succinylcholine to facilitate tracheal intubation in neonates

open access: yesAin Shams Journal of Anesthesiology, 2021
Use of succinylcholine in neonates is surrounded by many controversies. The need to review this topic stems from the fact that though there is an abundance of information, but there are divergent views regarding its use in neonates.
Bhavna Gupta, Priyanka Mishra
doaj   +1 more source

THE NATURE OF ACETYLCHOLINE RECEPTOR [PDF]

open access: yesActa Medica Iranica, 1983
The present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. AChE molecules stand at the gate of this
M.E. TASHAYOD
doaj   +1 more source

Extreme Paralysis Following Rocuronium Administration in a Myasthenia Gravis Patient: A Case Report

open access: yesClinical Practice and Cases in Emergency Medicine, 2023
Introduction: The use of paralytics during rapid sequence intubation (RSI) in patients with myasthenia gravis (MG) remains a controversial topic in emergency medicine.
Kelsey Billups   +2 more
doaj   +1 more source

Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1976
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was ...
R, Hughes, J P, Payne, N, Sugai
openaire   +2 more sources

Anaesthetic management in a patient with multiple sclerosis

open access: yesIndian Journal of Anaesthesia, 2011
Multiple sclerosis (MS) is a rare autoimmune demyelinating disorder of the central nervous system clinically manifesting as periodic attacks of varied neurologic symptoms, eventually progressing to fixed neurologic deficits and disability.
Lata M Kulkarni   +3 more
doaj   +1 more source

EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON PERIPHERAL AUTONOMIC MECHANISMS IN CATS

open access: yesBritish Journal of Anaesthesia, 1976
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with effects on autonomic mechanisms in anaesthetized cats. Whereas autonomic blockade with tubocurarine occurred at parasympathetic and sympathetic ganglia, neuromuscular paralysing doses of gallamine, alcuronium, pancuronium and fazadinium caused blockade at vagal ...
R, Hughes, D J, Chapple
openaire   +2 more sources

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