Results 41 to 50 of about 3,526 (188)

Optimizing Organ Donation After Euthanasia: A Critical Appraisal

Transplantology
This Critical Appraisal aims to explore the pharmacokinetics and pharmacodynamics of medications used in organ donors after euthanasia (ODE) and their impact on abdominal organ quality.
E. A. J. Alkemade, H. D. Lam, B. J. C. Hendriks, A. E. Braat, I. P. J. Alwayn, M. J. Coenraad, A. G. Baranski   +6 more
doaj   +1 more source

Neuromuscular Blockade Monitoring: Having It but Knowing When Not to Trust It [PDF]

, 2023
Butyrylcholinesterase (BChE) is an enzyme involved in the degradation of depolarizing and non-depolarizing neuromuscular blocking agents (NMBA), such as succinylcholine and mivacurium, respectively. Its deficiency is inherited or acquired, and results in
Esteves, Simão, Frada, Rita, Campos, Matilde, Salvador, Sara   +3 more
core   +1 more source

Effects of Neostigmine and Sugammadex for Reversal of Neuromuscular Blockade on QT Dispersion Under Propofol Anesthesia: A Randomized Controlled Trial

Cardiology and Therapy, 2018
Introduction Reversal of non-depolarizing neuromuscular blocking agent neostigmine is associated with QT prolongation under general anesthesia. To clarify the effects of neostigmine and sugammadex on hemodynamic status, the QT interval and QT dispersion ...
Yusuke Yamashita, Toshifumi Takasusuki, Yoshiyuki Kimura, Makoto Komatsuzaki, Shigeki Yamaguchi   +4 more
doaj   +1 more source

Biomimetic 3D Tactile Sensor System With Neuromorphic Encoding for Fascicle‐Level Feedback

Advanced Intelligent Systems, EarlyView.
A 3D biomimetic tactile sensor system converts skin‐like mechanical interactions into neural stimulation‐ready spike patterns. Embedded slow‐ and fast‐adapting sensors distinguish sustained pressure from transient touch, while neuromorphic encoding preserves their temporal signatures.
Minseok Kim, Jaeu Park, Minseok Kang, Yongwoo Kim, Sanghoon Lee   +4 more
wiley   +1 more source

Steroidal neuromuscular blocking agents

, 1998
Since 1964 approximately 20 steroidal neuromuscular blocking agents have been evaluated clinically. Pancuronium, a bisquaternary compound designed on the drawingboard, was the first steroidal relaxant introduced into clinical practice worldwide in the ...
Toyooka, H, Shingu, K, Ohmura, A, Hatano, Y, Wierda, JMKH, Mori, K, Fukuda, K   +6 more
core   +2 more sources

Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent

Theranostics, 2019
Succinylcholine (Sch) is the only depolarizing neuromuscular blocking agent widely used for rapid sequence induction in emergency rooms. Unfortunately, a variety of (sometimes lethal) adverse effects, such as hyperkalemia and cardiac arrest, are associated with its use, and currently there are no specific antidotes to reverse Sch or to treat these side-
Zhang, Xiangjun, Cheng, Qian, Li, Lanlan, Shangguan, Liqing, Li, Chenwen, Li, Shengke, Huang, Feihe, Zhang, Jianxiang, Wang, Ruibing   +8 more
openaire   +2 more sources

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Recurrent Hyperkalemia During General Anesthesia in a Dog

Frontiers in Veterinary Science, 2020
Objective: To describe the development of recurrent hyperkalemia in a dog that underwent general anesthesia at two different hospitals within a month. The definitive underlying cause of the hyperkalemia remains unknown.Case summary: A 11 year-old male ...
Carissa W. Tong, Anusha Balakrishnan, Rachel Matusow Wynne   +2 more
doaj   +1 more source

EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON THE CARDIAC VAGUS NERVE IN THE GUINEAPIG

British Journal of Anaesthesia, 1980
The ability of gallamine, metocurine, pancuronium, tubocurarine and atropine to block the response to postganglionic stimulation of the vagus nerve were measured in isolated, spontaneously beating guineapig atria. From analysis of the results in conjunction with those of earlier assays of concentrations that block effects of preganglionic vagal ...
S L, Son, D R, Waud
openaire   +2 more sources

Perioperative Adverse Events in Primary Palatoplasty: “Risk Factors and Impact on Care Escalation in a Multicenter Cohort”

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Patients undergoing palatoplasty experience perioperative adverse events. Identifying risk factors for perioperative adverse events and escalation of care may improve outcomes. Methods Pediatric patients undergoing primary palatoplasty were included in this retrospective observational study performed at two academic children's ...
Febina Padiyath, Elizabeth M. O'Brien, Jennifer Nam, Paula Hu, Nishil Mehta, Marc Parris, Anthony Alexander, Ashley Hodges, Goretti Chiang, Vinícius Caldeira Quintão, Ricardo Vieira Carlos, Gabriel Soares de Sousa, Asif Padiyath, Susan C. Nicolson, John Fiadjoe, Oksana A. Jackson, Lisa K. Lee, Annery G. Garcia‐Marcinkiewicz   +17 more
wiley   +1 more source