Neuromuscular depolarizing agents

Results 51 to 60 of about 6,015 (212)

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Use and Outcomes of Sugammadex for Neurological Examination after Neuromuscular Blockade in the Emergency Department

Western Journal of Emergency Medicine
Introduction: Non-depolarizing agents such as rocuronium and vecuronium are frequently used in the emergency department (ED) to facilitate intubation but may lead to delay in neurologic examination and intervention.
Stephen D. Hallisey +4 more
doaj +1 more source

Anesthesia Management of Duchenne Muscular Dystrophy with Complete Atrioventricular Block in Angiography Laboratory

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2018
Duchenne muscular distrophy is an X-linked, recessive, inherited genetic disorder, which is seen in 1/3500 of the population and characterized by progressive muscle degeneration and contractures.
Ahmet Onat Bermede +5 more
doaj +1 more source

Identification of Multiple Functional Receptors for Tyramine on an Insect Secretory Epithelium [PDF]

, 2017
The biogenic amine tyramine (TA) regulates many aspects of invertebrate physiology and development. Although three TA receptor subtypes have been identified (TAR1-3), specific receptors have not been linked to physiological responses in native tissue. In
Blumenthal, Edward M, Zhang, Haiying
core +2 more sources

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source

The effect of magnesium on the reversal of rocuronium-induced neuromuscular block with sugammadex: an ex vivo laboratory study

BMC Anesthesiology, 2019
Background Magnesium dose-dependently potentiates the effect of non-depolarizing neuromuscular blocking agents. We investigated whether the potentiation of rocuronium-induced blockade by magnesium reduces the effect of sugammadex in an ex-vivo ...
Ákos I. Fábián +4 more
doaj +1 more source

Compared efficacy and tolerance of the neuromuscular blockade induced by brand-name (Nimbex®) and generic (Cisatrex®) of cisatracurium in mechanically ventilated critically ill patients: a crossover double-blind randomized study

The Pan African Medical Journal, 2020
INTRODUCTION: Use of generic drugs is common. However, there is still concern among patients and physicians that brand name drugs are more efficient. The aim of the study was to compare efficacy and tolerance between two forms of cisatracurium: brand ...
Nesrine Fraj +5 more
doaj +1 more source

Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent

Theranostics, 2019
Succinylcholine (Sch) is the only depolarizing neuromuscular blocking agent widely used for rapid sequence induction in emergency rooms. Unfortunately, a variety of (sometimes lethal) adverse effects, such as hyperkalemia and cardiac arrest, are associated with its use, and currently there are no specific antidotes to reverse Sch or to treat these side-
Zhang, Xiangjun +8 more
openaire +2 more sources

Error Traps in Pediatric Neuromuscular Block

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Neuromuscular blocking agents are essential for safe pediatric anesthesia but remain a frequent source of preventable morbidity when misused, inadequately monitored, or incompletely reversed. Children, particularly neonates and infants, are especially vulnerable to residual neuromuscular block due to developmental pharmacological ...
Gabriel Soares de Sousa +5 more
wiley +1 more source

Are prehospital airway management resources compatible with difficult airway algorithms? A nationwide cross-sectional study of helicopter emergency medical services in Japan [PDF]

, 2016
PURPOSE: Immediate access to the equipment required for difficult airway management (DAM) is vital. However, in Japan, data are scarce regarding the availability of DAM resources in prehospital settings.
Goto, Aya +14 more
core +1 more source

neuromuscular nondepolarizing agents
humans
3. good health

animals
neuromuscular blocking agents
neuromuscular junction

female
rocuronium
sugammadex