Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: prospective propensity score matched cohort study [PDF]
Objective: To determine whether use of intermediate acting neuromuscular blocking agents during general anesthesia increases the incidence of postoperative respiratory complications. Design: Prospective, propensity score matched cohort study.
Ehrenfeld, Jesse M. +9 more
core +1 more source
Barriers and aids to routine neuromuscular monitoring and consistent reversal practice—A qualitative study [PDF]
Background: Neuromuscular monitoring is recommended whenever a neuromuscular blocking agent is administered, but surveys have demonstrated inconsistent monitoring practices.
Marty, Adrian P +6 more
core +3 more sources
Malignant hyperthermia – state of knowledge
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke +6 more
doaj +1 more source
Use of succinylcholine in neonates is surrounded by many controversies. The need to review this topic stems from the fact that though there is an abundance of information, but there are divergent views regarding its use in neonates.
Bhavna Gupta, Priyanka Mishra
doaj +1 more source
Extreme Paralysis Following Rocuronium Administration in a Myasthenia Gravis Patient: A Case Report
Introduction: The use of paralytics during rapid sequence intubation (RSI) in patients with myasthenia gravis (MG) remains a controversial topic in emergency medicine.
Kelsey Billups +2 more
doaj +1 more source
THE NATURE OF ACETYLCHOLINE RECEPTOR [PDF]
The present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. AChE molecules stand at the gate of this
M.E. TASHAYOD
doaj +1 more source
Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was ...
R, Hughes, J P, Payne, N, Sugai
openaire +2 more sources
Anaesthetic management in a patient with multiple sclerosis
Multiple sclerosis (MS) is a rare autoimmune demyelinating disorder of the central nervous system clinically manifesting as periodic attacks of varied neurologic symptoms, eventually progressing to fixed neurologic deficits and disability.
Lata M Kulkarni +3 more
doaj +1 more source
Clinical Pharmacology of the Neuromuscular Blocking Agents
Neuromuscular blocking agents are among the most commonly used drugs during general anesthesia. They compete with acetylcholine and interfere with the transmission of nerve impulses resulting in skeletal muscle relaxation.
Irwin Gratz +3 more
core +1 more source
EFFECTS OF NON-DEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS ON PERIPHERAL AUTONOMIC MECHANISMS IN CATS
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with effects on autonomic mechanisms in anaesthetized cats. Whereas autonomic blockade with tubocurarine occurred at parasympathetic and sympathetic ganglia, neuromuscular paralysing doses of gallamine, alcuronium, pancuronium and fazadinium caused blockade at vagal ...
R, Hughes, D J, Chapple
openaire +2 more sources

