Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents [PDF]
AbstractAbstract Calabadion 2 rapidly reversed deep rocuronium-, vecuronium-, and cisatracurium-induced neuromuscular blockade in a dose-dependent manner. Calabadion 2 reversed rocuronium- and vecuronium-induced neuromuscularblockade with a 1:1 binding ratio, like sugammadex, but it had a higher in vitro binding affinity and a higher ...
Haerter, Friederike +11 more
openaire +4 more sources
Identification and Quantitation of Six Non-Depolarizing Neuromuscular Blocking Agents by LC-MS in Biological Fluids [PDF]
A liquid chromatography-electrospray-mass spectrometry technique for the screening and determination of five non-depolarizing neuromuscular blocking agents (NDBAs), atracurium and its product of degradation/metabolite laudanosine, rocuronium, pancuronium, vecuronium, and mivacurium has been developed using ambenonium as the internal standard (I.S ...
Hervé, Sayer +5 more
openaire +4 more sources
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Background: Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without risk and may result in accidental awareness under general anaesthesia and postoperative residual ...
Kamilla Pedersen +3 more
doaj +1 more source
Neuromuscular blockade management for intraoperative neural monitoring
This article reviews the literature on development of neuromuscular blockade management in thyroid surgery with intraoperative neural monitoring (IONM) in the past decade.
I‐Cheng Lu +2 more
doaj +1 more source
Pharmacodynamic interactions between muscle relaxants and other medications in practice of anesthesia [PDF]
Knowledge of drug interactions is an essential element of medical practice. Along with the increasing occurrence of multimorbidity and the associated multi-drug use, the number of possible combinations of preparations is constantly rising.
Paweł Radkowski, Rafał Marek Okoński
doaj +1 more source
Rocuronium-Sugammadex in Anesthesia for Electroconvulsive Therapy [PDF]
Electroconvulsive therapy (ECT) is a form of treatment which is very effective in many psychiatric disorders. The administration of anesthesia plays a positive role in the success of ECT and improves the oxygenation of the body during the process ...
Nilay Tas, Esra Yancar Demir
doaj +1 more source
(1) Background: Pancuronium bromide is a neuromuscular blocker used for immobilizing crocodiles that can be reversed with neostigmine. A recommended drug dose has only been established for saltwater crocodiles (Crocodylus porosus), mostly based on trials
Lionel Schilliger +6 more
doaj +1 more source
Neuromuscular blockers and their reversal: have we finally found the on-off switches?
Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah +3 more
doaj +1 more source
Sugammadex, a selective antagonist of steroidal non‐depolarizing neuromuscular blocking agents, has been used in children in limited circumstances. However, neither pharmacokinetics (PKs) nor recovery profile of sugammadex for intense neuromuscular ...
Sang‐Hwan Ji +8 more
doaj +1 more source
Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]
Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri +36 more
core +1 more source

