Results 81 to 90 of about 3,526 (188)

Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]

open access: yes, 2008
The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core  

CLINICAL OBSERVATIONS ON THE NEUROMUSCULAR BLOCKING ACTION OF ORG 9426, A NEW STEROIDAL NON-DEPOLARIZING AGENT

open access: yesBritish Journal of Anaesthesia, 1990
The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been investigated in anaesthetized patients. Based on data from a pilot study, two doses, 250 and 500 micrograms kg-1 (estimated as the ED90 and 2 x ED90, respectively) were chosen.
WIERDA, JMKH   +3 more
openaire   +3 more sources

Nicotinic transmission and drugs in anesthesia : neuromuscular blocking agents and propofol : consequences for carotid body function

open access: yes, 2006
The carotid body is the global oxygen sensor of the human body. Acute hypoxia elicits instant hyperventilation mediated from the carotid body type 1 cells, where nicotinic transmission is a key component in oxygen sensing and signalling.
Malin Jonsson (19525729)
core  

Analysis of Clinical Outcomes and Cost-Effectiveness of Neuromuscular Blocking Drug Reversal in Patients with Obstructive Sleep Apnea

open access: yes, 2022
Non-depolarizing neuromuscular blockers are used during many surgical procedures to induce muscle relaxation for tracheal intubation and improve surgical conditions for surgeons. The use of these medications requires an agent to be given to fully reverse
Kinglsey, Samantha, Corn, Aaron Mitch
core   +1 more source

Neuromuscular Blockade: Offset Anomalies. Are they Simply Potency-related Receptor Bonding Effects?

open access: yes, 1997
Rapid making and breaking of bonds between quaternary ammonium compounds and cholinergic receptors is typical of ion-pair bonding, which is weak, and ion-pair reactions, which are extremely fast.
John B Stenlake, John M Midgley
core   +1 more source

Muscle relaxants in paediatric day case surgery

open access: yes, 2001
It has been estimated that more than 60% of all paediatric surgery is performed on a day case basis. The benefits of this type of surgery in children include reduced costs, avoidance of the stress of hospitalization and less disruption to family life ...
Meakin, G. H.
core   +1 more source

A novel approach to reversal of neuromuscular blockade

open access: yes, 2009
Postoperative residual curarization is still a problem of the modern anesthesia. Neostigmine is not the safest drug that allows a safe decurarization, especially when neuromuscular transmission monitoring is not used.
DELLA ROCCA, Giorgio, Pompei L.
core  

The prejunctional inhibitory effect of suramin on neuromuscular transmission in vitro

open access: yes, 1996
The P2 purinoceptor antagonist suramin reverses skeletal muscle paralysis evoked by non-depolarizing neuromuscular blocking agents in vitro and in vivo. To further study the action of suramin on neuromuscular transmission, (miniature) endplate potentials
Braga, M. Fatima M.   +19 more
core   +1 more source

Ajánlás az izomrelaxánsok biztonságos perioperatív használatára = Guideline on the safe use of neuromuscular blocking agents

open access: yes
Az izomrelaxánsok nem megfelelő használatából adódó posztoperatív residualis neuromuscularis blokk (PORNB) napjainkban továbbra is jelentős probléma, amely a posztoperatív pulmonalis szövődmények önálló kockázati tényezője.
Asztalos, László   +13 more
core   +1 more source

Neuromuscular effects of rapacuronium on the diaphragm and skeletal muscles in anaesthetized patients using cervical magnetic stimulation for stimulating the phrenic nerves

open access: yes, 2002
Background and objective: Non-depolarizing neuromuscular blocking agents have a shorter duration of action on the diaphragm than on skeletal muscles.
Hinz, Jose Maria   +4 more
core   +1 more source

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