Results 81 to 90 of about 3,526 (188)
Design and synthesis of modified peptide antibiotics of the vancomycin family [PDF]
The ability of bacteria to constantly evolve new methods of resistance to antibacterial therapies represents a constant challenge in medicine. Emergence of strains of enterococci and S. Aureus that show resistance to vancomycin is an alarming phenomenon,
Bone, Philip Andrew
core
The neuromuscular blocking effects of Org 9426, the 2-morpholino, 16-allyl-pyrrolidino derivative of the 3-desacetoxy analogue of vecuronium have been investigated in anaesthetized patients. Based on data from a pilot study, two doses, 250 and 500 micrograms kg-1 (estimated as the ED90 and 2 x ED90, respectively) were chosen.
WIERDA, JMKH +3 more
openaire +3 more sources
The carotid body is the global oxygen sensor of the human body. Acute hypoxia elicits instant hyperventilation mediated from the carotid body type 1 cells, where nicotinic transmission is a key component in oxygen sensing and signalling.
Malin Jonsson (19525729)
core
Non-depolarizing neuromuscular blockers are used during many surgical procedures to induce muscle relaxation for tracheal intubation and improve surgical conditions for surgeons. The use of these medications requires an agent to be given to fully reverse
Kinglsey, Samantha, Corn, Aaron Mitch
core +1 more source
Neuromuscular Blockade: Offset Anomalies. Are they Simply Potency-related Receptor Bonding Effects?
Rapid making and breaking of bonds between quaternary ammonium compounds and cholinergic receptors is typical of ion-pair bonding, which is weak, and ion-pair reactions, which are extremely fast.
John B Stenlake, John M Midgley
core +1 more source
Muscle relaxants in paediatric day case surgery
It has been estimated that more than 60% of all paediatric surgery is performed on a day case basis. The benefits of this type of surgery in children include reduced costs, avoidance of the stress of hospitalization and less disruption to family life ...
Meakin, G. H.
core +1 more source
A novel approach to reversal of neuromuscular blockade
Postoperative residual curarization is still a problem of the modern anesthesia. Neostigmine is not the safest drug that allows a safe decurarization, especially when neuromuscular transmission monitoring is not used.
DELLA ROCCA, Giorgio, Pompei L.
core
The prejunctional inhibitory effect of suramin on neuromuscular transmission in vitro
The P2 purinoceptor antagonist suramin reverses skeletal muscle paralysis evoked by non-depolarizing neuromuscular blocking agents in vitro and in vivo. To further study the action of suramin on neuromuscular transmission, (miniature) endplate potentials
Braga, M. Fatima M. +19 more
core +1 more source
Az izomrelaxánsok nem megfelelő használatából adódó posztoperatív residualis neuromuscularis blokk (PORNB) napjainkban továbbra is jelentős probléma, amely a posztoperatív pulmonalis szövődmények önálló kockázati tényezője.
Asztalos, László +13 more
core +1 more source
Background and objective: Non-depolarizing neuromuscular blocking agents have a shorter duration of action on the diaphragm than on skeletal muscles.
Hinz, Jose Maria +4 more
core +1 more source

