Results 71 to 80 of about 1,601,842 (182)
A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]
Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox Michael A +12 more
core +1 more source
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
MXene Bioinks for 3D Bioprinting: Design and Translation
This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac +2 more
wiley +1 more source
Non-depolarizing neuromuscular blocking agents (NMBAs) are commonly used in human anesthesia but remain uncommon in veterinary medicine. This study evaluated the effects of 0.5 mg/kg cisatracurium IV on muscle relaxation, cardiovascular variables and ...
Claudia Interlandi +7 more
doaj +1 more source
Incidence of postoperative residual neuromuscular blockade: a prospective observational study
Introduction: The use of non-depolarizing neuromuscular blockers (ND-NMB) is essential in anesthetic management as it improves ventilation conditions, airway management, and surgical conditions.
Diego Luis Vélez-Agudelo +3 more
doaj +1 more source
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega +6 more
wiley +1 more source
Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
M. Galvan +5 more
core +1 more source
Interactions between suxamethonium and non-depolarizing neuromuscular blocking-drugs [PDF]
In anaesthetized cats, we have confirmed that previously injected suxamethonium potentiates non-depolarizing neuromuscular blocking drugs whereas, when injected during the block, suxamethonium antagonizes the paralysis. We have attempted to explain these
Law, LW +171 more
core +3 more sources
Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine [PDF]
We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity
Kevin H. Hobbs +14 more
core +2 more sources
Neuromuscular blockade and reversal
Over the past 70 years since the introduction of d-tubocurarine, the search for an ideal neuromuscular blocking agent has led to the development of the depolarizing drug, succinylcholine (suxamethonium), with its rapid onset of action and plasma ...
Thomas Fuchs-Buder, Jennifer M. Hunter
core +1 more source

