Identification and quantitation of six non-depolarizing neuromuscular blocking agents by LC-MS in biological fluids. [PDF]
A liquid chromatography-electrospray-mass spectrometry technique for the screening and determination of five non-depolarizing neuromuscular blocking agents (NDBAs), atracurium and its product of degradation/metabolite laudanosine, rocuronium, pancuronium, vecuronium, and mivacurium has been developed using ambenonium as the internal standard (I.S ...
Pierre Marquet +2 more
exaly +3 more sources
Presumptive mivacurium chloride-associated histamine release resulting in overt tissue edema during endoscopic thyroidectomy: a report of two cases [PDF]
Background Recently, endoscopic thyroid surgeries have gained popularity for the treatment of thyroid tumors. Mivacurium chloride is a highly selective non-depolarizing neuromuscular blocking agent with a short duration of action.
Chun Jin +6 more
doaj +2 more sources
ObjectiveTo evaluate the association between neuromuscular blockade agent (NMBA) use and outcome in dogs undergoing mechanical ventilation (MV), including survival to discharge, and complications.MethodsThe medical records for 227 mechanically ventilated
Lena Ngo +9 more
doaj +3 more sources
Abstract Objectives To describe the prevalence of use of non-depolarizing neuromuscular blockers/relaxants by anesthesiologists in our area, and the perception of anesthesiologists in the Valle del Cauca region with regards to monitoring. Methodology A descriptive, cross-sectional study including 258 anesthesiologists, and a review of the data ...
Lema Flórez, Eduardo +2 more
exaly +2 more sources
Farmacocinética y farmacodinamia del bromuro de rocuronio: Influencia de la terapia crónica con fenitoína. [PDF]
[spa] ANTECEDENTES: La administración crónica de fármacos antiepilépticos disminuye la intensidad del efecto de los fármacos bloqueantes neuromusculares (BNM), aunque existe cierta discrepancia a la hora de explicar si esta interacción se produce a nivel
Fernández Candil, Juan Luís
core +6 more sources
Sugammadex administration in patients with end-stage renal disease: a narrative review with recommendations [PDF]
Due to unknown safety concerns, sugammadex should not be administered to patients with end-stage renal disease (ESRD). However, because the supply of benzylisoquinolinium-type neuromuscular blocking agents (NMBAs) has been discontinued, rocuronium is the
Seok Kyeong Oh, Byung Gun Lim
doaj +1 more source
Sugammadex: clinical development and practical use [PDF]
Sugammadex is belonging to a new class of drugs: the selective relaxant binding agents. Sugammadex can reverse residual paralysis by encapsulating free circulating non depolarizing muscle relaxants.
Thomas Fuchs-Buder +2 more
doaj +1 more source
Current clinical application of dantrolene sodium [PDF]
Dantrolene sodium (DS) was first introduced as an oral antispasmodic drug. However, in 1975, DS was demonstrated to be effective for managing malignant hyperthermia (MH) and was adopted as the primary therapeutic drug after intravenous administration ...
Hong Seuk Yang +5 more
doaj +1 more source
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Background: Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without risk and may result in accidental awareness under general anaesthesia and postoperative residual ...
Kamilla Pedersen +3 more
doaj +1 more source
The effect of non-depolarizing neuromuscular blocking agents on the release of acetylcholine from the right atrium of the guinea pig. [PDF]
The effect of various non-depolarizing neuromuscular blocking agents (gallamine, pancuronium, vecuronium, d-tubocurarine, metocurine, atracurium and pipecuronium) on [3H]acetylcholine release in the response to field electrical stimulation was investigated in vitro in preparations of the guinea pig right atrium.
Manabe, Nobuki
openaire +4 more sources

