Results 151 to 160 of about 666,453 (371)

The Role of Muscle microRNAs in Repairing the Neuromuscular Junction

open access: yesPLoS ONE, 2014
microRNAs have been implicated in mediating key aspects of skeletal muscle development and responses to diseases and injury. Recently, we demonstrated that a synaptically enriched microRNA, miR-206, functions to promote maintenance and repair of the ...
Gregorio Valdez   +3 more
semanticscholar   +1 more source

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

open access: yesChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti   +4 more
wiley   +1 more source

Acetylcholine receptors in regenerating muscle accumulate at original synaptic sites in the absence of the nerve. [PDF]

open access: yes, 1979
We examined the role of nerve terminals in organizing acetylcholine receptors on regenerating skeletal-muscle fibers. When muscle fibers are damaged, they degenerate and are phagocytized, but their basal lamina sheaths survive.
Burden, SJ, McMahan, UJ, Sargent, PB
core  

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino   +3 more
wiley   +1 more source

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

open access: yesEpilepsia Open, EarlyView.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier   +8 more
wiley   +1 more source

Monitoring the Neuromuscular Junction [PDF]

open access: yesAnaesthesia and Intensive Care, 1988
Cass Nm, Beemer Gh
openaire   +3 more sources

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Intelligent flexible memristors for artificial synapses and neuromorphic computing

open access: yesFlexMat, EarlyView.
Overview of the Structure and Principle, Research Status, and Application Prospects of Flexible Memristor Materials (All relevant copyrights are listed in the following text). Abstract Memristors have garnered significant attention in the field of non‐volatile memory devices due to their excellent characteristics such as miniaturization, low power ...
Qingyao Mao   +3 more
wiley   +1 more source

Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila [PDF]

open access: yes, 1997
The neural receptor tyrosine phosphatases DPTP69D, DPTP99A and DLAR are involved in motor axon guidance in the Drosophila embryo. Here we analyze the requirements for these three phosphatases in growth cone guidance decisions along the ISN and SNb ...
Desai, Chand J.   +3 more
core  

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