Results 171 to 180 of about 8,587 (262)

Effects of diltiazem on the crayfish neuromuscular junction

open access: diamond, 1979
Haruhiko Shinozaki, Michiko Ishida
openalex   +1 more source

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

open access: yesCell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang   +9 more
wiley   +1 more source

Pelvic Floor Muscle Function Recovery Using Biofabricated Tissue Constructs with Neuromuscular Junctions

open access: green, 2020
Ji Hyun Kim   +6 more
openalex   +1 more source

Interventions for children with developmental coordination disorder: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This scoping review identified 13 differing categories of interventions delivered to children with developmental coordination disorder worldwide ranging from task oriented, motor skills training, and sensorimotor approaches to sports training approaches and health promotion, with motor performance mostly reported as outcome and similar effectiveness ...
Dorothee Jelsma   +9 more
wiley   +1 more source

Surgical management of recurrent oesophageal obstruction in a yearling Saddlebred filly

open access: yesEquine Veterinary Education, EarlyView.
Summary This case report describes the diagnostic approach and surgical management of a yearling Saddlebred filly with recurrent oesophageal obstruction, likely caused by an acquired extraluminal oesophageal stricture. The filly initially presented with repeated episodes of oesophageal obstruction, which were resolved with sedation and nasogastric ...
K. M. Andrews   +4 more
wiley   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

open access: yesThe FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna   +5 more
wiley   +1 more source

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

open access: yesThe FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong   +6 more
wiley   +1 more source

Intravesical Botox: An Effective Therapy for Refractory Monosymptomatic Nocturnal Enuresis

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Monosymptomatic nocturnal enuresis (MNE) significantly impacts many children, with substantial patient groups refractory to conventional first‐line treatments. Intravesical Botox is used for various refractory functional voiding disorders in children, but its efficacy in MNE has not been widely established.
Eliza Szwarcberg   +2 more
wiley   +1 more source

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