Results 171 to 180 of about 77,782 (191)

Salbutamol repurposing ameliorates neuromuscular junction defects and muscle atrophy in Col6a1-/- mouse model of collagen VI-related myopathies. [PDF]

open access: yesClin Transl Med
Calabrò S   +11 more
europepmc   +1 more source

The Impact of the COVID‐19 Pandemic on Physical, Social and Emotional Well‐Being in a Cohort of Children With Disabilities in the United States

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background The COVID‐19 pandemic has affected the daily lives of all individuals. Research is limited in how children with disabilities (CWD) in the United States (U.S.) have been affected by the pandemic socially or emotionally, or if they are obtaining the recommended 60 min of daily physical activity.
Cara Vernacchia   +10 more
wiley   +1 more source

Enteric neuropathy and the vagus nerve: Therapeutic implications

open access: yesNeurogastroenterology &Motility, EarlyView.
Abstract Enteric neuropathies are characterized by abnormalities of gut innervation, which includes the enteric nervous system, inducing severe gut dysmotility among other dysfunctions. Most of the gastrointestinal tract is innervated by the vagus nerve, the efferent branches of which have close interconnections with the enteric nervous system and ...
Bruno Bonaz
wiley   +1 more source

The human colon: Evidence for degenerative changes during aging and the physiological consequences

open access: yesNeurogastroenterology &Motility, EarlyView.
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley   +1 more source

Genomic stress in diseases stemming from defects in the second brain

open access: yesNeurogastroenterology &Motility, EarlyView.
The enteric nervous system, a.k.a., second brain, is subject to a range of genotoxic exposures that include intrinsic oxidative stress and extrinsic agents associated with ingested foods, inflammation, and dysbiosis. Resulting DNA damage, if left unrepaired, can induce cell dysfunction or death, resulting in gut abnormalities and enteric neuropathy ...
Lobke Marie M. Mombeek   +2 more
wiley   +1 more source

Future Applications of Central Neuromodulation and Neurophysiological Testing in Cyclic Vomiting Syndrome

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 3, March 2025.
ABSTRACT Background Cyclic vomiting syndrome (CVS) is defined by its episodic patterning. Furthermore, CVS is associated with other episodic disorders such as migraine and epilepsy. Indeed, many of the medications that are known to be useful for prophylaxis and abortive therapy in CVS are also effective in preventing and aborting migraines and seizures.
David J. Levinthal, Braden Kuo
wiley   +1 more source

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