Serum levels of matrix metalloproteinases-2 and-9 and their tissue inhibitors in inflammatory neuromuscular disorders [PDF]
We monitored serum levels of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) before and during intravenously applied immunoglobulin (IVIG) therapy in 33 patients with chronic immune-mediated neuropathies and myopathies and 15 ...
B.G.H. Schoser +15 more
core +1 more source
Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy [PDF]
BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disease resulting from mutations in the survival motor neuron 1 (SMN1) gene. Recent breakthroughs in preclinical research have highlighted several potential novel therapies for SMA, increasing ...
Gillingwater, T. H. +4 more
core +3 more sources
Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was ...
James J Lamberg, Joseph F Answine
doaj +1 more source
Respiratory and airway-protective muscle weakness caused by the blockade of neuromuscular transmission is a major cause of early mortality from snakebite envenoming (SBE).
Philip E. Bickler +3 more
doaj +1 more source
Neuromuscular blockade management in patients with COVID-19 [PDF]
This narrative review evaluates the evidence for using neuromuscular blocking agents (NMBA) in patients being treated for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Harold Chaves-Cardona +3 more
doaj +1 more source
Feasibility, drug safety, and effectiveness of etiological treatment programs for Chagas disease in Honduras, Guatemala, and Bolivia: 10-year experience of Médecins Sans Frontières [PDF]
BACKGROUND: Chagas disease (American trypanosomiasis) is a zoonotic or anthropozoonotic disease caused by the parasite Trypanosoma cruzi. Predominantly affecting populations in poor areas of Latin America, medical care for this neglected disease is often
Oliver Yun +35 more
core +2 more sources
The effect of hand dominance on neuromuscular monitoring at the adductor pollicis muscle [PDF]
BackgroundNeuromuscular blockade of the adductor pollicis muscle may be influenced by hand dominance resulting in conflicting results of several studies.
Ji Seon Jeong +5 more
doaj +1 more source
Background Complete avoidance of residual neuromuscular blockade (RNMB) during the postoperative period has not yet been achieved in current anesthesia practice.
Gonzalo Domenech +5 more
doaj +1 more source
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
core +1 more source
Deep Neuromuscular Blockade During General Anesthesia: Advantages, Challenges, and Future Directions
Background: Neuromuscular blocking agents play an important role in modern anesthesia by facilitating optimal surgical conditions through deep muscle relaxation.
Jacob Rosenberg, Thomas Fuchs-Buder
doaj +1 more source

