Treatment algorithm for infants diagnosed with spinal muscular atrophy through newborn screening [PDF]
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by the degeneration of alpha motor neurons in the spinal cord, leading to muscular atrophy.
Connolly, Anne +14 more
core +2 more sources
Biomechanics of foetal movement. [PDF]
© 2015, AO Research Institute. All rights reserved.Foetal movements commence at seven weeks of gestation, with the foetal movement repertoire including twitches, whole body movements, stretches, isolated limb movements, breathing movements, head and neck
Nowlan, NC
core +2 more sources
The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development [PDF]
Despite multiple publications on potential therapies for neuromuscular diseases (NMD) in cell and animal models only a handful reach clinical trials. The ability to prioritise drug development according to objective criteria is particularly critical in ...
Allen, Hugh +49 more
core +8 more sources
Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi +99 more
core +2 more sources
Diagnostic accuracy of Tensiomyography parameters for monitoring peripheral neuromuscular fatigue.
The diagnostic accuracy of tensiomyography (TMG) parameters compared to the gold standard in neuromuscular fatigue evaluation using voluntary and electrically induced muscle activation is unclear.
Miloš Kalc +4 more
semanticscholar +1 more source
Background and Aims: Obese patients are more vulnerable to residual neuromuscular block (NMB) and its associated complications in the post-operative period. This study was carried out to compare neostigmine induced reversal of vecuronium in normal weight,
Shilpa Bhimasen Joshi +2 more
doaj +1 more source
Adverse events of sugammadex that occurred in a Korean population [PDF]
Background With increasing use, the incidence of adverse events associated with sugammadex, a neuromuscular blockade reverser, is increasing. This study aimed to identify and analyze cases of adverse events caused by sugammadex reported in Korean ...
Woong Han +5 more
doaj +1 more source
Profile of sugammadex for reversal of neuromuscular blockade in the elderly: Current perspectives [PDF]
The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of ...
Bertoncello, Francesco +2 more
core +1 more source
Analysis of characteristics of patients whose sugammadex claims were denied by the Auto Insurance Claims Review Department of Korean Health Insurance Review & Assessment Service: a retrospective single-center review [PDF]
Background Recently, there have been many cases where sugammadex used in traffic accident patients has been deducted from auto insurance claims. This study aims to investigate the characteristics of sugammadex deductions through retrospective analysis ...
Hwa Song Jong, Ki Tae Jung
doaj +1 more source
Relationship between hearing function and myasthenia gravis: a contemporary review [PDF]
There is increasing evidence of a connection between hearing function and myasthenia gravis (MG). Studies of the pathophysiological basis of this relationship suggest that acetylcholine receptors (AChRs) on outer hair cells (OHCs) play a central role. In
ALTISSIMI, Giancarlo +5 more
core +1 more source

