Neuromuscular Disorders Affecting Neuromuscular Monitor Information
筋弛緩状態評価を行う際には, 神経筋病態が筋弛緩モニター情報に及ぼす影響を考慮する必要がある. 重症筋無力症やLambert-Eaton症候群等の神経筋接合部疾患では, 神経筋伝達機能低下のため筋弛緩薬の作用が増強される. Duchenne型筋ジストロフィーや筋緊張性ジストロフィー等の筋疾患や敗血症病態では筋線維のみならず神経筋接合部も障害されることがあり, 筋弛緩薬の作用増強がみられることがある. また筋収縮力が微弱な場合, 単収縮が長時間持続する場合, 興奮収縮連関に異常がある場合も, 筋弛緩モニター情報が不正確になることがある.
Eichi NARIMATSU +2 more
openaire +2 more sources
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Neurohormonal modulation of the Limulus heart: amine actions on neuromuscular transmission and cardiac muscle [PDF]
The responses of Limulus cardiac neuromuscular junctions and cardiac muscle cells to four endogenous amines were determined in order to identify the cellular targets underlying amine modulation of heartbeat amplitude.
Augustine, George J. +3 more
core +1 more source
Intraoperative Neurophysiological Monitoring for Endoscopic Endonasal Approaches to the Skull Base: A Technical Guide. [PDF]
Intraoperative neurophysiological monitoring during endoscopic, endonasal approaches to the skull base is both feasible and safe. Numerous reports have recently emerged from the literature evaluating the efficacy of different neuromonitoring tests during
Doan, Adam T. +6 more
core +3 more sources
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
BackgroundAlthough diaphragm ultrasound can be used for detecting residual neuromuscular blockade post-surgery, there exists notable dearth in contemporary research exploring the correlation between preoperative Child-Pugh classification and the ...
Yan Sun +20 more
doaj +1 more source
Not just small adults–practical pearls in pediatric anesthesia: a narrative review [PDF]
Pediatric anesthesia presents unique challenges due to children’s distinct physiological and anatomical characteristics, including variations in drug metabolism, airway structure, and respiratory and circulatory regulation.
Hee Young Kim
doaj +1 more source
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Background: Neuromuscular blocking agents are frequently administered to pigs used for research. In humans, administration of the drugs is not without risk and may result in accidental awareness under general anaesthesia and postoperative residual ...
Kamilla Pedersen +3 more
doaj +1 more source
A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J +17 more
core +2 more sources
Neuromuscular monitoring and its importance in neuromuscular blockade☆
Introduction: The incorporation of new guidelines or strategies as part of good practices in the use of muscle relaxants is not a requirement at present in the practice of anesthesia. There are only action recommendations designed to persuade clinicians of the fact that neuromuscular monitoring is a very useful tool for the rational use of muscle ...
Fabregat López, Joaquín +2 more
openaire +1 more source

