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Neuromyelitis optica (NMO) is a rare, idiopathic,inflammatory disease affecting the spine andcharacteristically sparing the brain. It mimics multiplesclerosis (MS) in many aspects.
Goyal V, Rooru S, Gafoor AS, Sreekala VK
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Neuromyelitis optica (NMO) or Devic′s disease was until recently regarded as an unusual or severe variant of multiple sclerosis. However the last decade has seen major advances in our understanding of the etiopathogenesis of NMO. Though unsettled,
Jacob Anu, Boggild Mike
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Neuromyelitis optica (NMO; also known as Devic syndrome) is a clinical syndrome characterized by attacks of acute optic neuritis and transverse myelitis. In most patients, NMO is caused by pathogenetic serum IgG autoantibodies to aquaporin 4 (AQP4), the most abundant water-channel protein in the central nervous system.
Sven, Jarius +5 more
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Neuromyelitis optica (NMO), formerly known as Devic disease, is an autoimmune astrocytopathic disease characterized by transverse myelitis and optic neuritis. Most patients demonstrate a relapsing course with incomplete recovery between attacks, resulting in progressive disability.
Sarah L, Patterson, Sarah E, Goglin
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Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disease of the central nervous system that is characterized mainly by recurrent optic neuritis and longitudinally extensive transverse myelitis. The aim of this article is to present current knowledge on the clinical features, diagnosis, pathogenesis and treatment of the condition.The article
Silje Agnethe Stokke, Kvistad +4 more
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The patient journey with NMOSD: From initial diagnosis to chronic condition
ObjectiveTo better understand the patient experience with neuromyelitis optica spectrum disorder (NMOSD) through the course of the illness.BackgroundNMOSD is a rare autoimmune disorder that causes recurrent inflammatory attacks of the optic nerve, spinal
Guillermo Delgado-Garcia +4 more
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Neuromyelitis Optica and Multiple Sclerosis are idiopathic inflammatory demyelinating diseases of the central nervous system that currently are considered distinct autoimmune diseases, so differences in genetic susceptibility would be expected.
Marcos Papais Alvarenga +9 more
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The discovery of serum autoantibodies against the astrocytic water channel aquaporin-4 (AQP4) as a biomarker of neuromyelitis optica (NMO, Devic syndrome) has revolutionized our understanding of this rare immune-mediated clinical entity and has provided a rationale for the use of therapeutic strategies targeting the humoral effector arm of autoimmune ...
B, Wildemann, S, Jarius, F, Paul
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Possibilities of therapy for neuromyelitis optica spectrum disorders
Neuromyelitis optica spectrum disorders are rare chronic autoimmune inflammatory demyelinating diseases of the central nervous system. Considering that the increase in neurological deficit in neuromyelitis optica spectrum disorders is mainly due to ...
E. S. Novikova
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Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain. [PDF]
INTRODUCTION: Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) are present in some neuromyelitis optica patients who lack antibodies against aquaporin-4 (AQP4-IgG). The effects of neuromyelitis optica MOG-IgG in the central nervous system
PJ Waters +29 more
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