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Neuromyelitis Optica [PDF]

open access: yesIndian Journal of Physical Medicine & Rehabilitation, 2009
Neuromyelitis optica (NMO) is a rare, idiopathic,inflammatory disease affecting the spine andcharacteristically sparing the brain. It mimics multiplesclerosis (MS) in many aspects.
Goyal V, Rooru S, Gafoor AS, Sreekala VK
doaj   +4 more sources

Neuromyelitis optica

open access: yesAnnals of Indian Academy of Neurology, 2007
Neuromyelitis optica (NMO) or Devic′s disease was until recently regarded as an unusual or severe variant of multiple sclerosis. However the last decade has seen major advances in our understanding of the etiopathogenesis of NMO. Though unsettled,
Jacob Anu, Boggild Mike
doaj   +5 more sources

Neuromyelitis optica [PDF]

open access: yesNature Reviews Disease Primers, 2020
Neuromyelitis optica (NMO; also known as Devic syndrome) is a clinical syndrome characterized by attacks of acute optic neuritis and transverse myelitis. In most patients, NMO is caused by pathogenetic serum IgG autoantibodies to aquaporin 4 (AQP4), the most abundant water-channel protein in the central nervous system.
Sven, Jarius   +5 more
  +8 more sources

Neuromyelitis Optica [PDF]

open access: yesRheumatic Disease Clinics of North America, 2017
Neuromyelitis optica (NMO), formerly known as Devic disease, is an autoimmune astrocytopathic disease characterized by transverse myelitis and optic neuritis. Most patients demonstrate a relapsing course with incomplete recovery between attacks, resulting in progressive disability.
Sarah L, Patterson, Sarah E, Goglin
  +9 more sources

Neuromyelitis optica [PDF]

open access: yesTidsskrift for Den norske legeforening, 2013
Neuromyelitis optica (NMO) is a rare autoimmune inflammatory disease of the central nervous system that is characterized mainly by recurrent optic neuritis and longitudinally extensive transverse myelitis. The aim of this article is to present current knowledge on the clinical features, diagnosis, pathogenesis and treatment of the condition.The article
Silje Agnethe Stokke, Kvistad   +4 more
  +5 more sources

The patient journey with NMOSD: From initial diagnosis to chronic condition

open access: yesFrontiers in Neurology, 2022
ObjectiveTo better understand the patient experience with neuromyelitis optica spectrum disorder (NMOSD) through the course of the illness.BackgroundNMOSD is a rare autoimmune disorder that causes recurrent inflammatory attacks of the optic nerve, spinal
Guillermo Delgado-Garcia   +4 more
doaj   +1 more source

Neuromyelitis optica is an HLA associated disease different from Multiple Sclerosis: a systematic review with meta-analysis

open access: yesScientific Reports, 2021
Neuromyelitis Optica and Multiple Sclerosis are idiopathic inflammatory demyelinating diseases of the central nervous system that currently are considered distinct autoimmune diseases, so differences in genetic susceptibility would be expected.
Marcos Papais Alvarenga   +9 more
doaj   +1 more source

Neuromyelitis optica

open access: yesAktuelle Neurologie, 2012
The discovery of serum autoantibodies against the astrocytic water channel aquaporin-4 (AQP4) as a biomarker of neuromyelitis optica (NMO, Devic syndrome) has revolutionized our understanding of this rare immune-mediated clinical entity and has provided a rationale for the use of therapeutic strategies targeting the humoral effector arm of autoimmune ...
B, Wildemann, S, Jarius, F, Paul
  +8 more sources

Possibilities of therapy for neuromyelitis optica spectrum disorders

open access: yesРусский журнал детской неврологии, 2022
Neuromyelitis optica spectrum disorders are rare chronic autoimmune inflammatory demyelinating diseases of the central nervous system. Considering that the increase in neurological deficit in neuromyelitis optica spectrum disorders is mainly due to ...
E. S. Novikova
doaj   +1 more source

Neuromyelitis optica MOG-IgG causes reversible lesions in mouse brain. [PDF]

open access: yes, 2013
INTRODUCTION: Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) are present in some neuromyelitis optica patients who lack antibodies against aquaporin-4 (AQP4-IgG). The effects of neuromyelitis optica MOG-IgG in the central nervous system
PJ Waters   +29 more
core   +4 more sources

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