Results 111 to 120 of about 311,459 (229)
Choroid Plexus Abnormalities in Autoimmune Encephalitis
Choroid plexus (ChP) enlargement is a robust AE imaging biomarker, with independent prognostic value for AEAE and poor outcomes. ChP MRI radiomic model predicts AEAE well, leveraging shape features to provide effective predictive performance for AEAE. Multi‑omics links ChP enlargement to reduced glutamatergic synapse pathway activity and enhanced PI3K ...
Yueqian Sun +4 more
wiley +1 more source
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Systemic lupus erythematosus is an autoimmune disease. Neuromyelitis optica (Devic’s disease) is an inflammatory disorder belonging to the central nervous system.
Asal Azami, Mohammadhassan Jokar
doaj
With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley +1 more source
The role of imaging in diagnosing neuromyelitis optica spectrum disorder
Early identification of neuromyelitis optica allows aggressive acute and prophylactic relapse management aimed at preventing disability. Since the discovery of pathogenic aquaporin-4 antibodies the neuromyelitis optica spectrum has widened significantly:
Palace, JA, Matthews, LA
core +1 more source
Introduction Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis.
Komolafe Morenikeji A +6 more
doaj +1 more source
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino +3 more
wiley +1 more source
Prognosis of Relapsing Neuromyelitis Optica
Clinical predictors of a relapsing course and subsequent survival in 80 patients with neuromyelitis optica (NMO) (57 relapsing, 23 monophasic) were developed from a study of medical records and patients at the Mayo Clinic, Scottsdale ...
J Gordon Millichap
core +1 more source
A case of multiple sclerosis detected by brain MRI during evaluation for modified electroconvulsive therapy in the long‐term course of schizophrenia. This case discusses the clinical overlap between multiple sclerosis pathology and treatment‐resistant schizophrenia. ABSTRACT Multiple sclerosis (MS) can present with neurological and psychiatric symptoms
Sho Miura +10 more
wiley +1 more source
ABSTRACT In the central nervous system (CNS), the tissue microenvironment is continuously monitored and regulated to secure the unobstructed function of neurons and of their networks. This is a key function of the neurovascular niche (NVN), which is the interface between the cells of the nervous tissue and the cells and the content of blood vessels. It
Ilias Kazanis +4 more
wiley +1 more source

