Results 91 to 100 of about 26,703 (203)

Fine specificity of antibodies against AQP4: Epitope mapping reveals intracellular epitopes [PDF]

, 2011
The autoantibody to aquaporin-4 (AQP4) is a marker and a pathogenetic factor in Neuromyelitis Optica (NMO) (Devic’s syndrome). Our aim was to identify B-cell antigenic linear epitopes of the AQP4 protein and investigate similarities with other molecules.
Alexopoulos, H., Dalakas, M. C., Kampylafka, E. I., Moutsopoulos, H. M., Routsias, J. G., Tzioufas, A. G.   +5 more
core   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee, Brian D. Adkins, Ayda Javanbakht, Hung S. Luu, Daniel K. Noland   +4 more
wiley   +1 more source

Reply to Letter: “Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring” by Saccà and Pelto Regarding “Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab”

Annals of Clinical and Translational Neurology, EarlyView.
Lea Gerischer, Jutta Schroeder‐Braunstein, Guido Wabnitz, Andreas Meisel   +3 more
wiley   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Neuromyelitis optica spectrum disorders in pediatric patients

Неврология, нейропсихиатрия, психосоматика, 2018
Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord.
Yu. V. Tokareva, A. S. Kotov, M. V. Panteleeva, M. S. Bunak   +3 more
doaj   +1 more source

Brainstem involvement - frequency, presentation and outcome [PDF]

, 2016
Background Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (ON) and/or myelitis.
Jarius, Sven, Kleiter, Ingo, Ruprecht, Klemens   +2 more
core   +1 more source

Therapeutic decision making in autoimmune and inflammatory disorders of the central nervous system in children. [PDF]

, 2016
Autoimmune and inflammatory disorders of the central nervous system can result in significant morbidity and mortality. Through the recognition of syndromes using diagnostic biomarkers, the clinician is now able to use immune suppressive therapies to ...
Dale, Rc, Lim, M., Nosadini, M
core  

Trends and Research Hotspots in Biomarkers of Sjögren's Syndrome Over the Past Two Decades: A Data‐Driven Atlas Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background Sjögren's syndrome (SS) is a chronic, systemic inflammatory disorder primarily characterized by dry eyes and dry mouth, often involving multiple organ systems. The disease's heterogeneous clinical presentation and the absence of non‐invasive, specific biomarkers complicate its diagnosis and prognostic assessment.
Xinyan Zhang, Huan Li, Xueqing Zhou, Shangwen Qi, Songwei Li   +4 more
wiley   +1 more source

Clinical evaluation of rituximab treatment for neuromyelitis optica

Neurología (English Edition), 2015
Introduction: Neuromyelitis optica is an inflammatory and usually relapsing demyelinating autoimmune disease of the central nervous system that targets the optic nerves and spinal cord. Rituximab has been used for different neurological diseases that are
M.J. Fernández-Megía, B. Casanova-Estruch, F. Pérez-Miralles, J. Ruiz-Ramos, C. Alcalá-Vicente, J.L. Poveda-Andrés   +5 more
doaj   +1 more source

Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination. [PDF]

, 2018
OBJECTIVE: We characterised the clinical course, treatment and outcomes in 59 patients with relapsing myelin oligodendrocyte glycoprotein (MOG) antibody-associated demyelination.
Australasian and New Zealand MOG Study Group Andrews, P, Barnett, Mh, Barton, J, Brilot, F, Broadley, S, Burrow, J, Butzkueven, H, Cairns, A, Calvert, S, Caruana, P, Chelakkadan, S, Clark, D, Dale, Rc, Fraser, C, Freeman, J, Fung, Vsc, Gill, D, Grattan-Smith, P, Gupta, S, Hardy, T, Henderson, Apd, Kothur, K, Lechner-Scott, J, Ling, S, Lopez, J, Malone, S, Marriott, M, Merheb, V, Mohammad, S, Nguyen, Tk, Nosadini, M, O'grady, G, Orr, C, Ouvrier, R, Parratt, J, Patrick, E, Pilli, D, Ramanathan, S, Reddel, Sw, Riminton, D, Riney, K, Rodriguez-Casero, V, Ryan, M, Scheffer, I, Shah, U, Shuey, N, Spooner, C, Subramanian, G, Tantsis, E, Tea, F, Thomas, T, Thompson, J, Troedson, C, Vucic, S, Ware, T, Webster, R, White, Ob, Yiannikas, C, Yiu, E, Zou, A.   +59 more
core   +1 more source