Results 91 to 100 of about 311,459 (229)

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

Efficacy and Safety of Rituximab in Pediatric Neuromyelitis Optica

, 2010
Neuromyelitis optica is a central nervous system disease characterized by optic neuritis and transverse myelitis. It is a devastating illness, and early treatment may prevent future relapses and severe disability.
Kenneth Silver, Michael Ko, Karen Onel, Naznin A. Mahmood, Adil Javed   +4 more
core   +1 more source

Update on neuromyelitis optica: natural history and management

, 2012
Panitha Jindahra1,2, Gordon T Plant1,21The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; 2St Thomas' Hospital, Westminster Bridge Road, London, UKAbstract: Neuromyelitis optica or Devic disease is an inflammatory ...
Jindahra P, Plant GT
core  

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Simultaneous T2, T2*, and R2′ Mapping for Multiple Sclerosis Using Nonlinear Model‐Based Reconstruction of Undersampled Radial RARE‐EPI MRI

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1872-1892, October 2026.
ABSTRACT Purpose To demonstrate the synergy of undersampled radial 2in1‐RARE‐EPI acquisition and nonlinear model‐based reconstruction for accelerated and simultaneous T2, T2*, and R2′ mapping in brains of patients with multiple sclerosis (MS). Methods 2in1‐RARE‐EPI combines a RARE module with an EPI module to capture T2 and T2* information.
Jose Raul Velasquez Vides, Carl J. J. Herrmann, Thomas Gladytz, Hoby P. Hetherington, Hendrik Mattern, Xiaoqing Wang, Jason M. Millward, Shahriar Shalikar, Igor Fabian Tellez Ceja, Beate Endemann, Sonia Waiczies, Joseph Kuchling, Friedemann Paul, Georg Rose, Min‐Chi Ku, Franz Schmitt, Thoralf Niendorf   +16 more
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorders: Diagnosis and Treatment

, 2011
The last decade has witnessed rapid developments in the clinical understanding and scientific foundation of neuromyelitis optica (NMO).curriculum_fellow; IC-E4cii1-relationships-between-optic-neuritis-and-multiple-sclerosis; IC-E4cii3-classification-and ...
Dean M. Wingerchuk, MD, MSc, FRCP(C)
core  

Clinical evaluation of rituximab treatment for neuromyelitis optica

Neurología (English Edition), 2015
Introduction: Neuromyelitis optica is an inflammatory and usually relapsing demyelinating autoimmune disease of the central nervous system that targets the optic nerves and spinal cord. Rituximab has been used for different neurological diseases that are
M.J. Fernández-Megía, B. Casanova-Estruch, F. Pérez-Miralles, J. Ruiz-Ramos, C. Alcalá-Vicente, J.L. Poveda-Andrés   +5 more
doaj   +1 more source

The Association of Apparent Myelin Water Fraction With Diffusional Kurtosis and Biophysical Modeling Parameters

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
We investigated associations between a panel of diffusion MRI metrics and myelin content, using ViSTa apparent myelin water fraction (aMWF) as a proxy for myelin. Fractional anisotropy (FA) showed a robust association with aMWF; however, more advanced metrics including radial kurtosis (K⊥) and axonal water fraction (f) had stronger correlations ...
Hunter G. Moss, Michael A. Sugarman, Jongho Lee, Andrew A. Chen, Jens H. Jensen, Andreana Benitez   +5 more
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder

, 2017
Over the past 13 years neuromyelitis optica spectrum disorder (NMOSD) has emerged as a discrete form of demyelinating disease of the central nervous system in which antibodies against a water channel found in high concentration on astrocytes are ...
Broadley, Simon, Clarke, Laura, Khalilidehkordi, Ellie, Heshmat, Saman   +3 more
core  

Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more [PDF]

, 2012
B cells and antibodies constitute an important element in different inflammatory diseases of the central nervous system (CNS). Autoantibodies can serve as a biomarker to identify disease subgroups and may in addition contribute to the pathogenic process.
Mayer, Marie Cathrin, Meinl, Edgar, Marie Cathrin Mayer, Edgar Meinl, Meinl, E., Mayer, M.   +5 more
core   +1 more source