Results 21 to 30 of about 1,209,467 (344)

Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]

open access: yes, 2015
Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core   +3 more sources

An Adaptive Locally Connected Neuron Model: Focusing Neuron

open access: yes, 2020
This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The model provides adaptive and differentiable local connectivity (plasticity) applicable to any domain.
Tek, F. Boray
core   +1 more source

Which Neurons Will Be the Engram - Activated Neurons and/or More Excitable Neurons? [PDF]

open access: yesExperimental Neurobiology, 2016
During past decades, the formation and storage principle of memory have received much attention in the neuroscience field. Although some studies have attempted to demonstrate the nature of the engram, elucidating the memory engram allocation mechanism was not possible because of the limitations of existing methods, which cannot specifically modulate ...
Ji-il Kim   +3 more
openaire   +3 more sources

A Stem Cell Model of the Motor Circuit Uncouples Motor Neuron Death from Hyperexcitability Induced by SMN Deficiency

open access: yesCell Reports, 2016
In spinal muscular atrophy, a neurodegenerative disease caused by ubiquitous deficiency in the survival motor neuron (SMN) protein, sensory-motor synaptic dysfunction and increased excitability precede motor neuron (MN) loss.
Christian M. Simon   +5 more
doaj   +1 more source

Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease

open access: yesMolecular Brain, 2021
Parkinson’s disease (PD) is a multi-system neurodegenerative disorder. Patients with PD often suffer chronic pain. In the present study, we investigated motor, sensory and emotional changes in three different PD mice models.
Zhaoxiang Zhou   +13 more
doaj   +1 more source

CMOS circuit implementations for neuron models [PDF]

open access: yes, 1990
The mathematical neuron basic cells used as basic cells in popular neural network architectures and algorithms are discussed. The most popular neuron models (without training) used in neural network architectures and algorithms (NNA) are considered ...
Linares Barranco, Bernabé   +2 more
core   +1 more source

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury [PDF]

open access: yesActa Neuropathologica Communications, 2015
Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity could have in facilitating interneuronal α-synuclein transfer and ...
Ulusoy, Ayse   +6 more
openaire   +4 more sources

The Effect of a Refractory Period on the Power Spectrum of Neuronal Discharge [PDF]

open access: yes, 1995
The interspike intervals in steady-state neuron firing are assumed to be independently and identically distributed random variables. In the simplest model discussed, each interval is assumed to be the sum of a random neuron refractory period and a ...
Bair, Wyeth, Franklin, Joel
core   +2 more sources

Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

open access: yesNature Communications, 2023
Spinal muscular atrophy is an autosomal recessive neuromuscular disease caused by mutations in the multifunctional protein Survival of Motor Neuron, or SMN.
Shaqraa Musawi   +15 more
doaj   +1 more source

The neurone. [PDF]

open access: yesPsychological Bulletin, 1915
n ...
openaire   +1 more source

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