Results 11 to 20 of about 472,963 (268)
Journal of Symbolic Computation, 2023 We apply methods of machine-learning, such as neural networks, manifold learning and image processing, in order to study 2-dimensional amoebae in algebraic geometry and string theory. With the help of embedding manifold projection, we recover complicated conditions obtained from so-called lopsidedness.
Jiakang Bao, Yang-Hui He, Edward Hirst
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Cold Spring Harbor Perspectives in Biology, 2009 The assembly of functional neuronal networks in the developing animal relies on the polarization of neurons, i.e., the formation of a single axon and multiple dendrites. Breaking the symmetry of neurons depends on cytoskeletal rearrangements. In particular, axon specification requires local dynamic instability of actin and stabilization of microtubules.
Tahirovic, S., Bradke, F.
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Molecular Brain, 2020 An amendment to this paper has been published and can be accessed via the original article.
Kohei Koga +10 more
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Nature Communications, 2022 Here, authors show that Smad3 acetylation via HDAC6 inhibition reverses Duchenne muscular dystrophy-like symptoms in the mdx mouse model, suggesting a potential therapeutic target for the disorder.
Alexis Osseni +10 more
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Molecular Brain, 2017 The tree shrew, as a primate-like animal model, has been used for studying high brain functions such as social emotion and spatial learning memory. However, little is known about the excitatory synaptic transmission in cortical brain areas of the tree ...
Xu-Hui Li +5 more
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Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex
Molecular Brain, 2020 Anterior cingulate cortex (ACC) plays important roles in sensory perception including pain and itch. Neurons in the ACC receive various neuromodulatory inputs from subcortical structures, including locus coeruleus noradrenaline (LC-NA) neurons.
Kohei Koga +10 more
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Microvascular decompression for hemifacial spasm: a review of twenty-one operated cases
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020 Background Microvascular decompression of facial nerve provides definitive and long-term cure for hemifacial spasm. We review our experience of treating hemifacial spasm by microvascular decompression.
Amey P. Patankar
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Cell Reports, 2016 In spinal muscular atrophy, a neurodegenerative disease caused by ubiquitous deficiency in the survival motor neuron (SMN) protein, sensory-motor synaptic dysfunction and increased excitability precede motor neuron (MN) loss.
Christian M. Simon +5 more
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Molecular Brain, 2020 Neuronal progenitor cells (NPC) play an essential role in homeostasis of the central nervous system (CNS). Considering their ability to differentiate into specific lineages, their manipulation and control could have a major therapeutic impact for those ...
Matteo Manzati +3 more
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Nature Communications, 2023 Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron loss, with additional pathophysiological involvement of non-neuronal cells such as microglia.
Björn F. Vahsen +18 more
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