Results 71 to 80 of about 1,209,467 (344)

An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature

Egyptian Journal of Neurosurgery, 2022
Background A Rathke’s cleft cyst is a benign intrasellar cystic lesion, with suprasellar extension reported in a few cases. An entirely suprasellar Rathke’s cleft cyst without any intrasellar component, though previously reported, is rare.
Amey P. Patankar, Shivani Chaudhary
doaj   +1 more source

Markov analysis of stochastic resonance in a periodically driven integrate-fire neuron

, 1998
We model the dynamics of the leaky integrate-fire neuron under periodic stimulation as a Markov process with respect to the stimulus phase. This avoids the unrealistic assumption of a stimulus reset after each spike made in earlier work and thus solves ...
A. Bulsara, A. Longtin, A. R. Bulsara, B. J. Gluckman, B. McNamara, C. F. Stevens, C. T. H. Baker, D. R. Cox, D. T. Gillespie, G. Bugmann, H. C. Tuckwell, H. E. Plesser, Hans E. Plesser, J. E. Levin, J. E. Rose, J. Feng, J. Franklin, J. G. Nicholls, J. J. Collins, J. J. Collins, J. K. Douglass, J. M. Goldberg, K. Wiesenfeld, K. Wiesenfeld, L. F. Abbott, L. Gammaitoni, L. Gammaitoni, L. Gammaitoni, M. B. Priestley, M. H. Choi, M. Stemmler, M. Stemmler, N. G. van Kampen, P. Cordo, P. Jung, P. Jung, P. Linz, P. Lánský, P. Maršálek, R. A. Lavine, R. Benzi, R. Kempter, R. Löfstedt, R. P. Morse, R. von Mises, S. M. Bezrukov, T. W. Troyer, T. Zhou, Theo Geisel, V. Berdichevsky, W. Bair, W. Gerstner, W. Kistler, Z. Gingl   +53 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Neuron as a Signal Processing Device

, 2014
A neuron is a basic physiological and computational unit of the brain. While much is known about the physiological properties of a neuron, its computational role is poorly understood.
Chklovskii, Dmitri B., Genkin, Alex, Hu, Tao, Pehlevan, Cengiz, Towfic, Zaid J.   +4 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

User expectations and experiences of an assistive robotic arm in amyotrophic lateral sclerosis: a multicenter observational study

Neurological Research and Practice
Objective Robotic arms are innovative assistive devices for ALS patients with progressive motor deficits of arms and hands. The objective was to explore the patients´ expectations towards a robotic arm system and to assess the actual experiences after ...
Susanne Spittel, Thomas Meyer, Ute Weyen, Torsten Grehl, Patrick Weydt, Robert Steinbach, Susanne Petri, Petra Baum, Moritz Metelmann, Anne-Dorte Sperfeld, Dagmar Kettemann, Jenny Norden, Annekathrin Rödiger, Benjamin Ilse, Julian Grosskreutz, Barbara Hildebrandt, Bertram Walter, Christoph Münch, André Maier   +18 more
doaj   +1 more source

SMN Is Essential for the Biogenesis of U7 Small Nuclear Ribonucleoprotein and 3′-End Formation of Histone mRNAs

Cell Reports, 2013
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by a deficiency in the survival motor neuron (SMN) protein. SMN mediates the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs) and possibly other RNPs.
Sarah Tisdale, Francesco Lotti, Luciano Saieva, James P. Van Meerbeke, Thomas O. Crawford, Charlotte J. Sumner, George Z. Mentis, Livio Pellizzoni   +7 more
doaj   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Inflammation in ALS and SMA: Sorting out the good from the evil

Neurobiology of Disease, 2010
Indices of neuroinflammation are found in a variety of diseases of the CNS including amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA).
Dimitra Papadimitriou, Virginia Le Verche, Arnaud Jacquier, Burcin Ikiz, Serge Przedborski, Diane B. Re   +5 more
doaj   +1 more source