Results 61 to 70 of about 635,756 (308)
Molecular Brain, 2020 Recent studies demonstrate that calcitonin gene-related peptide (CGRP) plays critical roles in migraine. Immunohistochemistry and in situ hybridization studies have shown that CGRP and its receptors are expressed in cortical areas that are critical for ...
Yinglu Liu +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Spermidine treatment: induction of autophagy but also apoptosis?
Molecular BrainMachado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3, is a fatal neurodegenerative disease that causes loss of balance and motor co-ordination, eventually leading to paralysis.
Maxinne Watchon +7 more
doaj +1 more source
The era of cryptic exons: implications for ALS-FTD
Molecular Neurodegeneration, 2023 TDP-43 is an RNA-binding protein with a crucial nuclear role in splicing, and mislocalises from the nucleus to the cytoplasm in a range of neurodegenerative disorders.
Puja R. Mehta +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Firing proprieties of an adaptive analog VLSI neuron [PDF]
, 2004 Ben Dayan Rubin D, Chicca E, Indiveri G. Firing proprieties of an adaptive analog VLSI neuron. Presented at the Proceedings of Bio-ADIT, Lausanne, Switzerland.We describe the response properties of a compact, low power, analog circuit that implements a ...
Ben Dayan Rubin, D. +2 more
core
, 2020 (Neuron 105, 212–216; January 22, 2020) In the original publication of this NeuroView, Pingping Li was omitted from the member list for the International Brain Initiative. This has now been corrected online.
Valdes-Sosa, Pedro A. +40 more
core +1 more source
Behavioral Simulation of Biological Neuron Systems in SystemC
, 2004 The investigation of neuron structures is an incredibly difficult and complex task that yields relatively low rewards in terms of information from biological forms (either animals or tissue).
Brown, Andrew D. +3 more
core +1 more source
An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature
Egyptian Journal of Neurosurgery, 2022 Background A Rathke’s cleft cyst is a benign intrasellar cystic lesion, with suprasellar extension reported in a few cases. An entirely suprasellar Rathke’s cleft cyst without any intrasellar component, though previously reported, is rare.
Amey P. Patankar, Shivani Chaudhary
doaj +1 more source