Results 51 to 60 of about 585,120 (318)

Multidimensional predictors of fatigue in amyotrophic lateral sclerosis: a cross-sectional study in China

open access: yesScientific Reports
This study aims to identify key predictors of fatigue in patients with amyotrophic lateral sclerosis (ALS) and examine the interaction of physiological, psychological, and social factors to inform management strategies.
Fangfang Cai   +8 more
doaj   +1 more source

Effects of sensorimotor learning on the human mirror neuron system [PDF]

open access: yes, 2009
The discovery, in the monkey, of “mirror” neurons, which fire in response both to the performance and to the observation of specific actions, has prompted extensive research into their properties, and into the possible functions of a putative mirror ...
Catmur, C, Catmur, C.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Dual roles of anterior cingulate cortex neurons in pain and pleasure in adult mice

open access: yesMolecular Brain, 2018
Human and animal studies indicate that some brain regions are activated during painful and pleasant situations, such as the anterior cingulate cortex (ACC).
Jing-Shan Lu   +4 more
doaj   +1 more source

An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents

open access: yeseLife, 2022
The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop   +4 more
doaj   +1 more source

Neurons other than motor neurons in motor neuron disease.

open access: yesHistology and histopathology, 2017
Amyotrophic lateral sclerosis (ALS) is typically defined by a loss of motor neurons in the central nervous system. Accordingly, morphological analysis for decades considered motor neurons (in the cortex, brainstem and spinal cord) as the neuronal population selectively involved in ALS.
Ruffoli R   +7 more
openaire   +5 more sources

Controlling oscillatory behaviour of a two neuron recurrent neural network using inputs [PDF]

open access: yes, 2001
Haschke R, Steil JJ, Ritter H. Controlling oscillatory behaviour of a two neuron recurrent neural network using inputs. In: Dorffner G, Bischof H, Hornik K, eds. Artificial Neural Networks - ICANN 2001. Lecture notes in computer science.
Dorffner, Georg   +5 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Towards the neurocomputer: an investigation of VHDL neuron models [PDF]

open access: yes, 2010
The investigation of neuron structures is an incredibly difficult and complex task that yields relatively low rewards in terms of information from biological forms (either animals or tissue).
Bailey, Julian A., Bailey, Julian A
core  

Technical performance and diagnostic utility of the new Elecsys (R) neuron-specific enolase enzyme immunoassay [PDF]

open access: yes, 2003
This international multicenter study was designed to evaluate the technical performance of the new double-monoclonal, single-step Elecsys neuron-specific enolase (NSE) enzyme immunoassay (EIA) and to assess its utility as a sensitive and specific test ...
Pawel, Joachim von   +25 more
core   +1 more source

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