Results 51 to 60 of about 1,014,356 (296)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Spin-Based Neuron Model with Domain Wall Magnets as Synapse
, 2012 We present artificial neural network design using spin devices that achieves ultra low voltage operation, low power consumption, high speed, and high integration density.
Augustine, Charles +3 more
core +1 more source
Subthreshold dynamics of a single neuron from a Hamiltonian perspective [PDF]
, 2008 We use Hamilton's equations of classical mechanics to investigate the behavior of a cortical neuron on the approach to an action potential. We use a two-component dynamic model of a single neuron, due to Wilson, with added noise inputs.
Steyn-Ross, D. Alistair +1 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Detection of subthreshold pulses in neurons with channel noise
, 2008 Neurons are subject to various kinds of noise. In addition to synaptic noise, the stochastic opening and closing of ion channels represents an intrinsic source of noise that affects the signal processing properties of the neuron.
A. L. Hodgkin +14 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Brain, 2020 Recent studies demonstrate that calcitonin gene-related peptide (CGRP) plays critical roles in migraine. Immunohistochemistry and in situ hybridization studies have shown that CGRP and its receptors are expressed in cortical areas that are critical for ...
Yinglu Liu +5 more
doaj +1 more source
, 2011 A simple threshold model of neuron firing (with the neuron membrane electrochemical potential governed by the chaotic Rossler attractor) has been analyzed by mapping the generated irregular spiking time-series into telegraph signals.
Bershadskii, A., Ikegaya, Y.
core +1 more source
Observability and Synchronization of Neuron Models [PDF]
, 2017 Observability is the property that enables to distinguish two different locations in $n$-dimensional state space from a reduced number of measured variables, usually just one.
Aguirre, Luis A. +2 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source