Results 81 to 90 of about 1,818,525 (389)

An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature

open access: yesEgyptian Journal of Neurosurgery, 2022
Background A Rathke’s cleft cyst is a benign intrasellar cystic lesion, with suprasellar extension reported in a few cases. An entirely suprasellar Rathke’s cleft cyst without any intrasellar component, though previously reported, is rare.
Amey P. Patankar, Shivani Chaudhary
doaj   +1 more source

Chaotic neuron clock

open access: yes, 2011
A simple threshold model of neuron firing (with the neuron membrane electrochemical potential governed by the chaotic Rossler attractor) has been analyzed by mapping the generated irregular spiking time-series into telegraph signals.
Bershadskii, A., Ikegaya, Y.
core   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Spermidine treatment: induction of autophagy but also apoptosis?

open access: yesMolecular Brain
Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3, is a fatal neurodegenerative disease that causes loss of balance and motor co-ordination, eventually leading to paralysis.
Maxinne Watchon   +7 more
doaj   +1 more source

SMN Is Essential for the Biogenesis of U7 Small Nuclear Ribonucleoprotein and 3′-End Formation of Histone mRNAs

open access: yesCell Reports, 2013
Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by a deficiency in the survival motor neuron (SMN) protein. SMN mediates the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs) and possibly other RNPs.
Sarah Tisdale   +7 more
doaj   +1 more source

Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory

open access: yesJournal of Neuroscience, 2019
17β-estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2 is known to be made in neurons in the brain, but its precise functions in the brain are unclear.
Yujiao Lu   +11 more
semanticscholar   +1 more source

Neuronal migration

open access: yesMechanisms of Development, 2001
Like other motile cells, neurons migrate in three schematic steps, namely leading edge extension, nuclear translocation or nucleokinesis, and retraction of the trailing process. In addition, neurons are ordered into architectonic patterns at the end of migration. Leading edge extension can proceed at the extremity of the axon, by growth cone formation,
Lambert De Rouvroit, Catherine   +1 more
openaire   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

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