Results 261 to 270 of about 470,748 (305)
Some of the next articles are maybe not open access.
Immunocytochemical Analysis of Neuronal Differentiation
2003Fully understanding the phenotype of neurons in vivo involves examining their morphology, immunocytochemically analyzing their protein expression, examining their afferent and efferent integration into neuronal microcircuitry, and functionally examining their activity.
Sanjay S P, Magavi, Jeffrey D, Macklis
openaire +3 more sources
Differentiation of neuronal from non-neuronal Substance P
Regulatory Peptides, 2009Substance P (SP) originally found as a neuropeptide in capsaicin-sensitive sensory neurons, had more recently been identified in non-neuronal cells, especially under pathological conditions. Neuronal and non-neuronal SP may perform distinct functions. A simple technique to differentiate different SP sources is currently unavailable. Herein, we describe
Nuray, Erin, Ozkan, Ulusoy
openaire +2 more sources
Foxp2 regulates neuronal differentiation and neuronal subtype specification
Developmental Neurobiology, 2014ABSTRACTMutations of the transcription factor FOXP2 in humans cause a severe speech and language disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or ultrasonic vocalization, respectively. These data suggest that Foxp2 plays important roles in the developing nervous system.
Yi-Chi, Chiu +5 more
openaire +2 more sources
Specification and differentiation of serotonergic neurons
Stem Cell Reviews, 2006Serotonin is an important neurotransmitter with multiple functions in the whole central nervous system. Its synthesis, however, is restricted to a very limited number of cells in the brainstem raphe nuclei with a vast axonal network. These cells express markers of the serotonin lineage such as the rate-limiting enzyme in serotonin synthesis, tryptophan
Natalia, Alenina +2 more
openaire +2 more sources
Immunocytochemical Phenotype of Differentiating Neurons
2015Immunohistochemistry techniques have been extensively used to identify and colocalize several proteins in neuronal specimens. A challenging task is the specifi c labeling of neuroepithelial -deriving cells in the course of neurogenesis . On the basis of the time-dependent expression of several molecular signals named as early, intermediate, or late ...
DIANA, ANDREA, CARAI, ANTONIO
openaire +1 more source
Neuronal nitric oxide synthase expression in neuronal cell differentiation
Neuroscience Letters, 1996Expression of neuronal nitric oxide synthase (n-NOS) was investigated during neuronal cell differentiation. Trace amounts of n-NOS mRNA were detected in the primary culture of neural precursor cell (NPC) at embryonic day 10, and a high level of n-NOS mRNA was observed after a further 7 days cultivation of NPC.
T, Ogura +3 more
exaly +3 more sources
Neuronal differentiation in the Drosophila ommatidium
Developmental Biology, 1987Using monoclonal and polyclonal antibodies as differentiation markers, we have found that the eight photoreceptors of the Drosophila ommatidium differentiate in a fixed sequence. The foundation photoreceptor, R8, expresses neural antigens first. The paired photoreceptors R2/5 are next to express, followed by the pair R3/4, followed by the pair R1/6; R7
A, Tomlinson, D F, Ready
openaire +2 more sources
Differentiation of Cochlear Afferent Neurons
Acta Oto-Laryngologica, 1981In order to clarify some open questions, the various types of afferent neurons of the cochlea were analysed in various species regarding their structural features, their association with outer or inner hair cells and their connection to the CNS, by means of degeneration experiments and tracer studies.
openaire +2 more sources
Drosophila Neuron Differentiation in Vitro
1971Many investigators have described the growth of axons in vitro from explants of embryonic mammalian or bird tissue (Murray, 1965). In all cases the explant contained cells from already differentiated nervous tissue and no claims were made for neuron differentiation from stem cells.
R L, Seecof, R L, Teplitz
openaire +2 more sources
Acetylcholine synthesis and neuron differentiation.
The International journal of developmental biology, 2000Development of the nervous system is dependent on the co-operation between cell determination events and the action of epigenetic factors; in addition to well known factors, e.g. growth factors, neurotransmitters have been assigned a role as "morphogens" and modulators of neuronal differentiation in an early developmental phase.
BIAGIONI, Stefano +3 more
openaire +2 more sources