Results 1 to 10 of about 276,634 (267)

Regional Development of Glioblastoma: The Anatomical Conundrum of Cancer Biology and Its Surgical Implication

open access: yesCells, 2022
Glioblastoma (GBM) are among the most common malignant central nervous system (CNS) cancers, they are relatively rare. This evidence suggests that the CNS microenvironment is naturally equipped to control proliferative cells, although, rarely, failure of
Ciro De Luca   +5 more
doaj   +1 more source

Micropatterning neuronal networks [PDF]

open access: yesThe Analyst, 2014
A simple and effective method for patterning primary neuronal networks and circuits.
Hardelauf, Heike   +8 more
openaire   +3 more sources

Super-Selective Reconstruction of Causal and Direct Connectivity With Application to in vitro iPSC Neuronal Networks

open access: yesFrontiers in Neuroscience, 2021
Despite advancements in the development of cell-based in-vitro neuronal network models, the lack of appropriate computational tools limits their analyses.
Francesca Puppo   +3 more
doaj   +1 more source

Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior

open access: yesMolecular Brain, 2022
Calsyntenins (CLSTNs) are important synaptic molecules whose molecular functions are not fully understood. Although mutations in calsyntenin (CLSTN) genes have been associated with psychiatric disorders in humans, their function is still unclear.
Keita Mori   +8 more
doaj   +1 more source

Communication in Neuronal Networks [PDF]

open access: yesScience, 2003
Brains perform with remarkable efficiency, are capable of prodigious computation, and are marvels of communication. We are beginning to understand some of the geometric, biophysical, and energy constraints that have governed the evolution of cortical networks.
Simon B, Laughlin, Terrence J, Sejnowski
openaire   +2 more sources

Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

open access: yesMolecular Brain, 2020
Protrudin is a protein that resides in the membrane of the endoplasmic reticulum and is highly expressed in the nervous system. Although mutations in the human protrudin gene (ZFYVE27, also known as SPG33) give rise to hereditary spastic paraplegia (HSP),
Michiko Shirane   +7 more
doaj   +1 more source

Neuronal and network activity in networks of cultured spinal motor neurons [PDF]

open access: yesNeuroReport, 2009
This is the first report of multielectrode recordings from networks of cultured motor neurons. Neurons isolated from the ventral horns of spinal cords of E15 rats were cultured on MED64 probes. The majority of the neurons in the cultures are positive for neurofilament, choline acetyltransferase, and Hb9, characteristics of motor neurons.
Hong-Mei, Zhang   +4 more
openaire   +2 more sources

The Synchronization Behaviors of Memristive Synapse-Coupled Fractional-Order Neuronal Networks

open access: yesIEEE Access, 2021
The synchronization behaviors of memristive synapse-coupled fractional-order neuronal networks are investigated in this paper. Based on the integer-order memristive synapse-coupled neuronal network, a fractional-order model is proposed, and a ring ...
Yang Xin, Zhang Guangjun
doaj   +1 more source

Parallel network simulations with NEURON [PDF]

open access: yesJournal of Computational Neuroscience, 2006
The NEURON simulation environment has been extended to support parallel network simulations. Each processor integrates the equations for its subnet over an interval equal to the minimum (interprocessor) presynaptic spike generation to postsynaptic spike delivery connection delay.
Michele Migliore   +4 more
openaire   +3 more sources

Observability of neuronal network motifs [PDF]

open access: yes2012 46th Annual Conference on Information Sciences and Systems (CISS), 2012
We quantify observability in small (3 node) neuronal networks as a function of 1) the connection topology and symmetry, 2) the measured nodes, and 3) the nodal dynamics (linear and nonlinear). We find that typical observability metrics for 3 neuron motifs range over several orders of magnitude, depending upon topology, and for motifs containing ...
Andrew J. Whalen   +3 more
openaire   +2 more sources

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