Results 21 to 30 of about 274,989 (217)

Impact of Neuronal Membrane Damage on the Local Field Potential in a Large-Scale Simulation of Cerebral Cortex

Frontiers in Neurology, 2017
Within multiscale brain dynamics, the structure–function relationship between cellular changes at a lower scale and coordinated oscillations at a higher scale is not well understood.
David L. Boothe, David L. Boothe, Alfred B. Yu, Pawel Kudela, Pawel Kudela, William S. Anderson, Jean M. Vettel, Jean M. Vettel, Jean M. Vettel, Piotr J. Franaszczuk, Piotr J. Franaszczuk   +10 more
doaj   +1 more source

Challenges in Reproducibility, Replicability, and Comparability of Computational Models and Tools for Neuronal and Glial Networks, Cells, and Subcellular Structures

Frontiers in Neuroinformatics, 2018
The possibility to replicate and reproduce published research results is one of the biggest challenges in all areas of science. In computational neuroscience, there are thousands of models available.
Tiina Manninen, Tiina Manninen, Jugoslava Aćimović, Jugoslava Aćimović, Riikka Havela, Riikka Havela, Heidi Teppola, Heidi Teppola, Marja-Leena Linne, Marja-Leena Linne   +9 more
doaj   +1 more source

The pulsatory liposome works as a neuronal network (I) [PDF]

INCAS Bulletin
In this paper we consider a unilamellar liposome (lipid vesicle) filled with aqueous solution of osmotic solute. This liposome is introduced in a hypotonic aqueous medium of large dimensions.
Dumitru POPESCU, Diana Rodica RADNEF-CONSTANTIN, Valentin Ioan Remus NICULESCU   +2 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Response of a neuronal network computational model to infrared neural stimulation

Frontiers in Computational Neuroscience, 2022
Infrared neural stimulation (INS), as a novel form of neuromodulation, allows modulating the activity of nerve cells through thermally induced capacitive currents and thermal sensitivity ion channels. However, fundamental questions remain about the exact
Jinzhao Wei, Jinzhao Wei, Licong Li, Licong Li, Hao Song, Hao Song, Zhaoning Du, Zhaoning Du, Jianli Yang, Jianli Yang, Mingsha Zhang, Mingsha Zhang, Mingsha Zhang, Xiuling Liu, Xiuling Liu   +14 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Fluorescence microscopy shadow imaging for neuroscience

Frontiers in Cellular Neuroscience
Fluorescence microscopy remains one of the single most widely applied experimental approaches in neuroscience and beyond and is continuously evolving to make it easier and more versatile.
V. V. G. Krishna Inavalli, Virginia Puente Muñoz, Virginia Puente Muñoz, Jonathan E. Draffin, Jonathan E. Draffin, Jan Tønnesen, Jan Tønnesen, Jan Tønnesen, Jan Tønnesen   +8 more
doaj   +1 more source

Representation and Learning in Neuronal Networks: A Conceptual Nervous System Approach

Rambam Maimonides Medical Journal, 2011
The work presented in this review describes the use of large cortical networks developing ex vivo, in a culture dish, to study principles underlying synchronization, adaptation, learning, and representation in neuronal assemblies. The motivation to study
Danny Eytan
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Efficient Coding and Energy Efficiency Are Promoted by Balanced Excitatory and Inhibitory Synaptic Currents in Neuronal Network

Frontiers in Cellular Neuroscience, 2018
Selective pressure may drive neural systems to process as much information as possible with the lowest energy cost. Recent experiment evidence revealed that the ratio between synaptic excitation and inhibition (E/I) in local cortex is generally ...
Lianchun Yu, Lianchun Yu, Zhou Shen, Chen Wang, Yuguo Yu   +4 more
doaj   +1 more source