Results 41 to 50 of about 276,634 (267)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2017 Functionally related neurons assemble into connected networks that process and transmit electrochemical information. To do this in a coordinated manner, the number and strength of synaptic connections is tightly regulated.
Peter Verstraelen +7 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Schizophrenia-Mimicking Layers Outperform Conventional Neural Network Layers
Frontiers in Neurorobotics, 2022 We have reported nanometer-scale three-dimensional studies of brain networks of schizophrenia cases and found that their neurites are thin and tortuous when compared to healthy controls.
Ryuta Mizutani +7 more
doaj +1 more source
Learning in Networks of Cortical Neurons [PDF]
The Journal of Neuroscience, 2001 The results presented here demonstrate selective learning in a network of real cortical neurons. We focally stimulate the network at a low frequency (0.3–1 Hz) until a desired predefined response is observed 50 ± 10 msec after a stimulus, at which point the stimulus is stopped for 5 min.
G, Shahaf, S, Marom
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Frontiers in Computational Neuroscience, 2020 The topographic organization of afferents to the hippocampal CA3 subfield are well-studied, but their role in influencing the spatiotemporal dynamics of population activity is not understood.
Gene J. Yu +2 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Neuro-Immune Hemostasis: Homeostasis and Diseases in the Central Nervous System
Frontiers in Cellular Neuroscience, 2018 Coagulation and the immune system interact in several physiological and pathological conditions, including tissue repair, host defense, and homeostatic maintenance.
Ciro De Luca +6 more
doaj +1 more source
Post-embryonic Development of the Circadian Clock Seems to Correlate With Social Life Style in Bees
Frontiers in Cell and Developmental Biology, 2020 Social life style can influence many aspects of an animal’s daily life, but it has not yet been clarified, whether development of the circadian clock in social and solitary living bees differs.
Katharina Beer +1 more
doaj +1 more source