Results 1 to 10 of about 462,209 (295)

Age-related synaptic loss of the medial olivocochlear efferent innervation

Molecular Neurodegeneration, 2010
Age-related functional decline of the nervous system is consistently observed, though cellular and molecular events responsible for this decline remain largely unknown. One of the most prevalent age-related functional declines is age-related hearing loss
Schrader Angela, Lei Debin, Simmons Dwayne, Le Prell Colleen, Fu Benjamin, Chen Amelia B, Bao Jianxin   +6 more
doaj   +1 more source

Monosynaptic Retrograde Tracing From Prelimbic Neuron Subpopulations Projecting to Either Nucleus Accumbens Core or Rostromedial Tegmental Nucleus

Frontiers in Neural Circuits, 2021
The prelimbic (PL) region of the medial prefrontal cortex (mPFC) has been implicated in both driving and suppressing motivated behaviors, including cocaine-seeking in rats.
Adelis M. Cruz, Tabitha H. Kim, Rachel J. Smith, Rachel J. Smith   +3 more
doaj   +1 more source

Sensory nerves directly promote osteoclastogenesis by secreting peptidyl-prolyl cis-trans isomerase D (Cyp40)

Bone Research, 2023
Given afferent functions, sensory nerves have recently been found to exert efferent effects and directly alter organ physiology. Additionally, several studies have highlighted the indirect but crucial role of sensory nerves in the regulation of the ...
Junqin Li, Bin Liu, Hao Wu, Shuaishuai Zhang, Zhuowen Liang, Shuo Guo, Huijie Jiang, Yue Song, Xing Lei, Yi Gao, Pengzhen Cheng, Donglin Li, Jimeng Wang, Yang Liu, Di Wang, Nazhi Zhan, Jing Xu, Lin Wang, Guozhi Xiao, Liu Yang, GuoXian Pei   +20 more
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Transplantation of Xenopus laevis tissues to determine the ability of motor neurons to acquire a novel target. [PDF]

PLoS ONE, 2013
The evolutionary origin of novelties is a central problem in biology. At a cellular level this requires, for example, molecularly resolving how brainstem motor neurons change their innervation target from muscle fibers (branchial motor neurons) to neural
Karen L Elliott, Douglas W Houston, Bernd Fritzsch   +2 more
doaj   +1 more source

GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing

Frontiers in Neural Circuits, 2018
Sensory axon T-like branching (bifurcation) in neurons from dorsal root ganglia and cranial sensory ganglia depends on the molecular signaling cascade involving the secreted factor C-type natriuretic peptide, the natriuretic peptide receptor guanylyl ...
Steffen Wolter, Dorit Möhrle, Hannes Schmidt, Sylvia Pfeiffer, Dennis Zelle, Philipp Eckert, Michael Krämer, Robert Feil, Peter K. D. Pilz, Marlies Knipper, Lukas Rüttiger   +10 more
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Characterization of HA-tagged α9 and α10 nAChRs in the mouse cochlea

Scientific Reports, 2020
Neurons of the medial olivary complex inhibit cochlear hair cells through the activation of α9α10-containing nicotinic acetylcholine receptors (nAChRs).
Pankhuri Vyas, Megan Beers Wood, Yuanyuan Zhang, Adam C. Goldring, Fatima-Zahra Chakir, Paul Albert Fuchs, Hakim Hiel   +6 more
doaj   +1 more source

Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice

Nature Communications, 2023
Stress management is necessary for vertebrate survival. Chronic stress drives depression by excitation of the lateral habenula (LHb), which silences dopaminergic neurons in the ventral tegmental area (VTA) via GABAergic neuronal projection from the ...
Soo Hyun Yang, Esther Yang, Jaekwang Lee, Jin Yong Kim, Hyeijung Yoo, Hyung Sun Park, Jin Taek Jung, Dongmin Lee, Sungkun Chun, Yong Sang Jo, Gyeong Hee Pyeon, Jae-Yong Park, Hyun Woo Lee, Hyun Kim   +13 more
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The Intrinsic Cardiac Nervous System: From Pathophysiology to Therapeutic Implications

Biology
The cardiac autonomic nervous system (CANS) plays a pivotal role in cardiac homeostasis as well as in cardiac pathology. The first level of cardiac autonomic control, the intrinsic cardiac nervous system (ICNS), is located within the epicardial fat pads ...
Giuseppe Giannino, Valentina Braia, Carola Griffith Brookles, Federico Giacobbe, Fabrizio D’Ascenzo, Filippo Angelini, Andrea Saglietto, Gaetano Maria De Ferrari, Veronica Dusi   +8 more
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Correction: Periaqueductal efferents to dopamine and GABA neurons of the VTA

PLOS ONE, 2019
[This corrects the article DOI: 10.1371/journal.pone.0190297.].
Niels R Ntamati, Meaghan Creed, Ridouane Achargui, Christian Lüscher   +3 more
openaire   +2 more sources

Unique nicotinic responses are present in distinct subtypes of mouse medial prefrontal layer V pyramidal neurons

Scientific Reports
The neurotransmitter acetylcholine supports goal-directed cognitive functions via activation of its nicotinic and muscarinic classes of receptors within the prefrontal cortex.
Ashutosh V. Patel, Anthony Nguyen, Ashley A. Geremia, Donia Zeng, Pietro Paletta, Elena Choleris, Craig D. C. Bailey   +6 more
doaj   +1 more source