Results 241 to 250 of about 1,725,183 (344)
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström +5 more
wiley +1 more source
Complex opioid-driven modulation of glutamatergic and cholinergic neurotransmission in a GABAergic brain nucleus associated with emotion, reward, and addiction. [PDF]
Chittajallu R +8 more
europepmc +1 more source
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Neurons of the precuneiform nucleus share structural and functional properties of the mesencephalic locomotor region. [PDF]
Pocsai K +5 more
europepmc +1 more source
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
Brain-Wide Connectivity Patterns of Feedforward and Feedback Cortico-Cortical Neurons in the Mouse Secondary Visual Cortex. [PDF]
Dickson RG +6 more
europepmc +1 more source
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher +8 more
wiley +1 more source
Cortical dopaminergic signaling mediates planning of directional movements. [PDF]
Chen J, Fontanini A.
europepmc +1 more source
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin +10 more
wiley +1 more source

