Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems
Journal of Neuroscience, 1998 The novel neuropeptides called hypocretins (orexins) have recently been identified as being localized exclusively in cell bodies in a subregion of the tuberal part of the hypothalamus.
C. Peyron +7 more
semanticscholar +1 more source
Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression [PDF]
, 2006 Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors
Berry, Carol +6 more
core +1 more source
Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges
eLife, 2022 Interictal epileptiform discharges (IEDs), also known as interictal spikes, are large intermittent electrophysiological events observed between seizures in patients with epilepsy.
Elliot H Smith +12 more
doaj +1 more source
eLife, 2021 Sex differences in whole-body fat storage exist in many species. For example, Drosophila females store more fat than males. Yet, the mechanisms underlying this sex difference in fat storage remain incompletely understood. Here, we identify a key role for
Lianna W Wat +4 more
doaj +1 more source
Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray [PDF]
, 2017 The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in
Bruchas, Michael R +7 more
core +2 more sources
Sexually dimorphic microRNA miR-190 regulates lifespan in male Drosophila
RNA Biology, 2022 microRNAs are short noncoding RNAs that buffer fluctuations in gene expression in a myriad of physiological conditions. Here, we carried out a screen to identify the role of microRNAs in the maintenance of age-dependent neuronal functions in adult ...
Jervis Fernandes, Jishy Varghese
doaj +1 more source
Journal of Neuroscience, 2008 Understanding the cell–cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate neural cell types.
John D. Cahoy +11 more
semanticscholar +1 more source
Which Neurons Will Be the Engram - Activated Neurons and/or More Excitable Neurons? [PDF]
Experimental Neurobiology, 2016 During past decades, the formation and storage principle of memory have received much attention in the neuroscience field. Although some studies have attempted to demonstrate the nature of the engram, elucidating the memory engram allocation mechanism was not possible because of the limitations of existing methods, which cannot specifically modulate ...
Ji-il Kim +3 more
openaire +3 more sources
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury [PDF]
Acta Neuropathologica Communications, 2015 Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity could have in facilitating interneuronal α-synuclein transfer and ...
Ulusoy, Ayse +6 more
openaire +4 more sources
Asymptotic description of stochastic neural networks. I - existence of a Large Deviation Principle [PDF]
, 2014 We study the asymptotic law of a network of interacting neurons when the number of neurons becomes infinite. The dynamics of the neurons is described by a set of stochastic differential equations in discrete time.
Faugeras, Olivier, MacLaurin, James
core +6 more sources