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Learning cellular morphology with neural networks
Nature Communications, 2019 Volume electron microscopy data of brain tissue can tell us much about neural circuits, but increasingly large data sets demand automation of analysis. Here, the authors introduce cellular morphology neural networks and successfully automate a range of ...
Philipp J. Schubert +4 more
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Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression [PDF]
, 2006 Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors
Berry, Carol +6 more
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Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems
Journal of Neuroscience, 1998 The novel neuropeptides called hypocretins (orexins) have recently been identified as being localized exclusively in cell bodies in a subregion of the tuberal part of the hypothalamus.
C. Peyron +7 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2020 Neurons derived from human induced pluripotent stem cells (hiPSC-derived neurons) offer novel opportunities for the development of preclinical models of human neurodegenerative diseases (NDDs).
Pedro Mateos-Aparicio +2 more
doaj +1 more source
Frontiers in Neuroanatomy, 2022 Glutamate acts as the main excitatory neurotransmitter in the brain and plays a vital role in physiological and pathological neuronal functions. In mammals, glutamate can cause detrimental excitotoxic effects under anoxic conditions.
Mohammad Tufazzal Hussan +3 more
doaj +1 more source
Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
, 1993 The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer +50 more
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Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. [PDF]
, 2017 Functional imaging and gene expression studies both implicate the medial prefrontal cortex (mPFC), particularly deep-layer projection neurons, as a potential locus for autism pathology.
Brumback, AC +9 more
core +1 more source
Which Neurons Will Be the Engram - Activated Neurons and/or More Excitable Neurons? [PDF]
Experimental Neurobiology, 2016 During past decades, the formation and storage principle of memory have received much attention in the neuroscience field. Although some studies have attempted to demonstrate the nature of the engram, elucidating the memory engram allocation mechanism was not possible because of the limitations of existing methods, which cannot specifically modulate ...
Ji-il Kim +3 more
openaire +3 more sources
Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray [PDF]
, 2017 The ventrolateral periaqueductal gray (vlPAG) constitutes a major descending pain modulatory system and is a crucial site for opioid-induced analgesia. A number of previous studies have demonstrated that glutamate and GABA play critical opposing roles in
Bruchas, Michael R +7 more
core +2 more sources