Results 61 to 70 of about 2,597,556 (387)
The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases,,
eNeuro, 2015 REST [RE1-silencing transcription factor (also called neuron-restrictive silencer factor)] is known to repress thousands of possible target genes, many of which are neuron specific.
P. Baldelli, J. Meldolesi
semanticscholar +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Walailak Journal of Science and Technology, 2013 Sphingosine-1-phosphate (S1P) is a bioactive lipid that signals through a family of G protein-coupled receptors, consisting of 5 members, termed S1P1, S1P2, S1P3, S1P4 and S1P5.
Chuchard PUNSAWAD
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Upper Limit on the Thermodynamic Information Content of an Action Potential
Frontiers in Computational Neuroscience, 2020 In computational neuroscience, spiking neurons are often analyzed as computing devices that register bits of information, with each action potential carrying at most one bit of Shannon entropy.
Sterling Street
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FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Vocalization Influences Auditory Processing in Collicular Neurons of the CF-FM-Bat, Rhinolophus ferrumequinum [PDF]
, 1979 1. In awake Greater Horseshoe bats (Rhinolophus ferrumequinum) the responses of 64 inferior colliculus neurons to electrically elicited vocalizations (VOC) and combinations of these with simulated echoes (AS: pure tones and AS(FM): sinusoidally ...
A.D. Grinnell +8 more
core +1 more source
Neural Regeneration Research, 2015 Mismatch negativity is generated automatically, and is an early monitoring indicator of neuronal integrity impairment and functional abnormality in patients with brain injury, leading to decline of cognitive function.
Hui-yan Sun +3 more
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Coiled-Coil Motifs of RNA-Binding Proteins: Dynamicity in RNA Regulation
Frontiers in Cell and Developmental Biology, 2020 Neuronal granules are biomolecular condensates that concentrate high quantities of RNAs and RNA-related proteins within neurons. These dense packets of information are trafficked from the soma to distal sites rich in polysomes, where local protein ...
Lenzie K. Ford, Luana Fioriti
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Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Frontiers in Molecular NeuroscienceThe synaptic proteome can be shaped by proteins transported from the neuronal soma and/or by mRNAs that are delivered to synapses where proteins are locally synthesized. This last mechanism is known as local translation.
Aida de la Cruz-Gambra +3 more
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