Results 81 to 90 of about 1,753,121 (371)

Cluster synchronization in an ensemble of neurons interacting through chemical synapses

, 2005
In networks of periodically firing spiking neurons that are interconnected with chemical synapses, we analyze cluster state, where an ensemble of neurons are subdivided into a few clusters, in each of which neurons exhibit perfect synchronization.
A. L. Hodgkin, M. Yoshioka, Masahiko Yoshioka, V. B. Mountcastle, X. J. Wang, Y. Kuramoto   +5 more
core   +1 more source

The role of insulin receptor substrate 2 in hypothalamic and β cell function [PDF]

, 2005
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in β cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Al-Qassab, H., Al-Qassab, H., Ashford, M.L.J., Ashford, M.L.J., Barsh, G.S., Barsh, G.S., Batterham, R.L., Batterham, R.L., Bedford, D.C., Bedford, D.C., Bell, J.D., Bell, J.D., Choudhury, A.I., Choudhury, A.I., Claret, M., Claret, M., Clements, M., Clements, M., Diakonov, I., Diakonov, I., Heffron, H., Heffron, H., Hisadome, K., Hisadome, K., MacColl, G., MacColl, G., Moosajee, V., Moosajee, V., Selman, C., Selman, C., Simmgen, M., Simmgen, M., Smith, M.A., Smith, M.A., Speakman, J.R., Speakman, J.R., Withers, D.J., Withers, D.J., Xu, A.W., Xu, A.W.   +39 more
core   +4 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley   +1 more source

Analyzing Autoencoder-Based Intrusion Detection System Performance

Journal of Information Security and Cybercrimes Research, 2023
The rise in cyberattacks targeting critical network infrastructure has spurred an increased emphasis on the development of robust cybersecurity measures.
Seiba Alhassan, Gaddafi Abdul-Salaam, Michael Asante, Yaw Missah, Ernest Ganaa   +4 more
doaj   +1 more source

Intervention effects of Ganoderma lucidum spores on epileptiform discharge hippocampal neurons and expression of Neurotrophin-4 and N-Cadherin [PDF]

, 2013
Epilepsy can cause cerebral transient dysfunctions. Ganoderma lucidum spores (GLS), a traditional Chinese medicinal herb, has shown some antiepileptic effects in our previous studies.
AA Ardelt, B Cheng, C Hyman, CG Wasterlain, CS von Bartheld, D Lobner, D Sliva, Di-Xiang Sun, DR Riddle, Fang-Fang Wang, FE Dudek, G Gobbi, GG Somjen, H Shibley, H Wang, Hemachandra Reddy, HT Zhang, Hui Wang, J Li, J Liu, JE Cavazos, Jia-Mei Wu, JP Leite, Jun-Xing Liu, K Sakuma, Lancet The, Lei Liu, M Engelhardt, M Engelhardt, M Fujita, MA Mikati, MW Chen, NC Royo, NY Ip, Peng-Fei Cheng, PS Buckmaster, Q Wang, R Bandopadhyay, R O'Mahony, S Sombati, S Zhao, Shaobo Zhou, Shu-Qiu Wang, T Su, TK Yun, U Treubert-Zimmermann, Xiao-Jie Li, Xiao-Ru Ma, Y Liu, Yan-Feng Liang, YH Chen, ZB Lin   +51 more
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Soma size distinguishes projection neurons from neurokinin 1 receptor-expressing interneurons in lamina I of the rat lumbar spinal dorsal horn [PDF]

, 2009
Lamina I of the spinal dorsal horn contains neurons that project to various brain regions, and ∼80% of these projection cells express the neurokinin 1 receptor (NK1r), the main receptor for substance P. Two populations of NK1r-immunoreactive neurons have
Al Ghamdi, K.S., Polgár, E., Todd, A.
core   +2 more sources

Neuronal migration

Mechanisms of Development, 2001
Like other motile cells, neurons migrate in three schematic steps, namely leading edge extension, nuclear translocation or nucleokinesis, and retraction of the trailing process. In addition, neurons are ordered into architectonic patterns at the end of migration. Leading edge extension can proceed at the extremity of the axon, by growth cone formation,
Lambert De Rouvroit, Catherine, Goffinet, André   +1 more
openaire   +3 more sources