Results 111 to 120 of about 114,925 (309)
Neuropathic pain: mechanisms of development, principles of diagnostics and treatment
Neuropathic pain is a pain caused by a disease or focal damage to the somatosensory nervous system. The prevalence of chronic pain with neuropathic features in different countries is estimated at 7–10 %.
Dmytro Dmytriiev +5 more
doaj +1 more source
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard +3 more
wiley +1 more source
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin +3 more
wiley +1 more source
Diagnostics and therapy of peripheral neuropathy (literature review)
The review is devoted to diagnostics and treatment of neuropathic pain in patients with peripheral nervous system diseases. Main assessment tools are shown including Visual analog Scale (VAS), Neuropathic Pain Scale (NPS), Leeds Assessment of Neuropathic
G. Y. Levina, Y. N. Bykov, A. S. Borisov
doaj
Can the neuropathic pain scale discriminate between non-neuropathic and neuropathic pain?
1) To determine if the neuropathic pain scale (NPS) can be used to classify chronic pain patients (CPPs) as having primarily neuropathic vs non-neuropathic pain, and furthermore; 2) to determine what, if any, cut-off score can be used to reliably make ...
Cutler, Robert +5 more
core +1 more source
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber +7 more
wiley +1 more source
Inhibition of Neuropathic Pain by a Potent Disintegrin - Triflavin
Injury to peripheral nerves may result in severe and intractable neuropathic pain. Many efforts have been focused on the elucidation of the mechanisms of neuropathic pain.
符文美;孫維仁;彭惠琴;劉鴻祺;黃德富 +1 more
core
DNMT3a methylation in neuropathic pain
Cuijie Shao, Yong Gao, Dan Jin, Xin Xu, Shuying Tan, Hui Yu, Qingxiang Zhao, Li Zhao, Wansheng Wang, Deqiang Wang Department of Pain, Binzhou Medical University Hospital, Binzhou, China Background: Mu opioid ...
Shao CJ +9 more
core
[Neurological Evaluation of Neuropathic Pain].
Neurological Evaluation of Neuropathic Pain Abstract. Neuropathic pain arises after lesions of the central or peripheral nervous system. The treatment of nociceptive pain - pain in which the somatosensory nervous system is intact - is different from ...
Scheidegger, Olivier, Blanquet, Marisa
core +1 more source
A middle‐aged man presented with a right indirect inguinal hernia in November 2020 and underwent laparoscopic high ligation of the right hernial sac. Intermittent acupuncture‐like pain in the skin of the right scrotum and medial thigh occurred 1 month after surgery and lasted for 6 months. Under ultrasound guidance, ilioinguinal nerve and genitofemoral
Yong Wang +4 more
wiley +1 more source

