Results 131 to 140 of about 1,094,883 (299)

Pain type and neuropathic pain components in acute herpes zoster

open access: yesAğrı
Objectives: The aim of this study was to investigate the pain type (nociceptive or neuropathic) and neuropathic pain components in patients with acute herpes zoster (HZ).
Hanzade Aybüke Ünal   +3 more
doaj   +1 more source

Low graft re‐rupture rate after primary ACL reconstruction using a modified MacIntosh iliotibial band technique with gracilis augmentation: Minimum 6‐year follow‐up

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Combined intra‐ and extra‐articular anterior cruciate ligament (ACL) reconstruction has gained renewed interest to improve rotational stability and reduce graft failure. This study evaluated graft re‐rupture rates, functional and return‐to‐sport (RTS) outcomes at a minimum 6‐year follow‐up after primary reconstruction using a modified ...
Baptiste Bouyge   +10 more
wiley   +1 more source

Increased mGluR5 in somatostatin-positive interneurons mediates deactivation of the mPFC in a mouse model of neuropathic pain

open access: yesExperimental and Molecular Medicine
Understanding the neurobiological alterations associated with neuropathic pain is crucial for treatment interventions, but the underlying mechanisms remain unclear.
Mirae Jang   +8 more
doaj   +1 more source

Challenging neuropathic pain syndromes : evaluation and evidence-based treatment /

open access: yes
Includes bibliographical references and index.Pathophysiology of pain -- Central sensitization, central sensitization syndromes, and chronic neuropathic pain -- A physiatric approach to the treatment of complex regional pain syndrome -- Complex regional ...
Gehret, Jeffrey A.,author.   +3 more
core  

Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats

open access: yes, 2015
Treating neuropathic pain continues to be a major clinical challenge and underlying mechanisms of neuropathic pain remain elusive. We have recently demonstrated that Wnt signaling, which is important in developmental processes of the nervous systems ...
Liu, Su   +6 more
core   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

open access: yesThe Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen   +3 more
wiley   +1 more source

Mechanisms of pain processing: spinal protein translation in the rat [PDF]

open access: yes, 2009
The word ‘pain’ is described by the International Association for the Study of Pain (IASP) as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.
Asante, C O, Asante, C.O.
core  

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud   +2 more
wiley   +1 more source

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

open access: yesMovement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota   +14 more
wiley   +1 more source

Neuropathic Pain

open access: yes, 2010
Neuropathic pain is one of the most difficult medical conditions to treat and although the primary goal is to alleviate pain, many clinicians now recognise that the most appropriate therapeutic goal may be to reduce pain to a more tolerable ...
Hall, Anthony
core  

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