Genetically‐targeted control of the spinal cord and peripheral nervous system
Application of genetically‐targeted stimulation for treating diseases or injuries outside the brain. Optogenetic and chemogenetic systems have been developed for dysfunction in the cochlea, spinal cord, dorsal root ganglia (DRGs), peripheral nerves, lower urinary tract, and enteric nervous system (ENS). Created with Biorender.com.
Anakaren Romero Lozano+3 more
wiley +1 more source
Diagnostics and therapy of peripheral neuropathy (literature review)
The review is devoted to diagnostics and treatment of neuropathic pain in patients with peripheral nervous system diseases. Main assessment tools are shown including Visual analog Scale (VAS), Neuropathic Pain Scale (NPS), Leeds Assessment of Neuropathic
G. Y. Levina, Y. N. Bykov, A. S. Borisov
doaj
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan+10 more
wiley +1 more source
Ultrasound Neuromodulation (Low‐Intensity Focused Ultrasound) to Treat Knee Osteoarthritis Pain
Low‐intensity focused ultrasound is a non‐invasive neuromodulation technique that delivers mechanical forces to a deep location within the body through acoustic pressure waves without affecting tissue between the transducer and focal target. Preliminary studies involving healthy volunteers suggest focused ultrasound reversibly prevents action potential
Brian M. Ilfeld+3 more
wiley +1 more source
A behavioural and pharmacological study of rats with chronic compressive sciatic mononeuropathy: an animal model of neuropathic pain [PDF]
Fernanda Edna Araújo Moura
openalex +1 more source
Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma
ABSTRACT Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma (ChARM) through the integration of evidence‐based research and multicenter clinical expertise, addresses ...
Qing Ji+112 more
wiley +1 more source
Abstract Aim This qualitative study aimed to identify nurses' and allied health professionals' perceptions and experiences of providing hospital‐acquired pressure injury (HAPI) prevention in a paediatric tertiary hospital in Australia, as well as understand the perceived barriers and facilitators to preventing HAPI.
Tanesha A. Dimanopoulos+6 more
wiley +1 more source
EPI-VALID : Validation of an algorithm for identifying patients with epilepsy in the SNDS using data from the CONSTANCES cohort [PDF]
Introduction: The HAS conducted a study in 2018 using the French National Health Data System (SNDS) on the care pathway of patients with epilepsy. This study used 2 algorithms to identify patients with epilepsy, based on hospitalization for epilepsy, insurance for chronic severe epilepsy, and antiepileptic drug (AE) dispensing, with exclusion of AEs ...
arxiv
Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients
Abstract Background Hereditary ataxias are genetically diverse, yet up to 75% remain undiagnosed due to technological and financial barriers. The GGC repeat expansion in ZFHX3, responsible for spinocerebellar ataxia type 4 (SCA4), has only been described in individuals of Northern Europeandescent.
Paula Saffie‐Awad+22 more
wiley +1 more source
Percutaneous electrical nerve stimulation: a novel analgesic therapy for diabetic neuropathic pain. [PDF]
May Hamza+8 more
openalex +1 more source